N/A N=56 Vitamin D Supplementation in Healthy Adolescents
Vitamin D Supplementation
Primary: Baseline 25 Hydroxy Vitamin D (25OHD) Levels — 28.1; 29 ng/ml
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=550 Topical Delivery of Vitamin D3 as Vitamin D Supplementation
Vitamin D Deficiency
Primary: Level of Serum 25 OHD Level Pre-treatment and Post Treatment — 12.03; 10.36; 37.17; 10.51 ng/mL — p=0.9
N/A N=43 Vitamin D Supplementation to Obese Chinese Males
Obesity · Insulin Resistance
Primary: Plasma 25-hydroxy Vitamin D (25(OH)D) Level (Nmol/L) — 116.7; 181.3; 46.1; 52.8 nmol/L
N/A N=81 Optimizing Vitamin D in the Elderly
Deficiency of Vitamin D3
Primary: Total 25-OH Vitamin D3 Level — 33; 34; 43; 61 ng/mL — p=<.0001
Phase 2 N=55 Supplementation With Cholecalciferol in Dialysis Patients
Chronic Kidney Disease
Primary: Change From Baseline in Interleukin-6 at 12 Weeks. — 9.0; 8.1; 9.6; 4.6 pg/mL
Phase 3 N=172 Vitamin D Supplementation in Multiple Sclerosis
Relapsing Remitting Multiple Sclerosis
Primary: Proportion of Subjects That Experience a Relapse — 0.32; 0.34 proportion of participants — p=0.60
Phase 2 N=114 Vitamin D3 Supplementation for Low-Risk Prostate Cancer: A Randomized Trial
Prostate Cancer
Primary: Pathology Status — 2.37; 1.73 number of positive cores
Phase 2 N=83 Vitamin D Supplementation in Veterans With Early-Stage Prostate Cancer
Prostate Cancer
Primary: PSA Slope (Trajectory) or the Change in PSA Level Over Time — 0.59; 0.27 ng/mL
N/A N=68 Improving Vitamin D Status in Home-bound Elders
Vitamin D Deficiency · Accidental Falls
Primary: Change in 25-hydroxyvitamin D Levels Over 5 Months — 21.7; 0 ng/mL
Phase 4 N=34 Effect of Vitamin D Supplementation on Muscle Mass and Function
Obesity · Insulin Resistance · Inflammation
Primary: Muscle Function — 1.14; 1.50 kilograms
N/A N=77 Vitamin D Supplementation on Cardiovascular Risk Factors
Type 2 Diabetes
Primary: Blood Lipid — 213.08; 193.88 mg/dl
N/A N=37 Efficacy of Vitamin D Supplementation in Bariatric Surgery Patients
Obesity · Vitamin D Deficiency
Primary: Vitamin D Concentrations, Pre Operative and Post Bariatric Surgery Following 12 Weeks of Vitamin D Supplementation — 19.1; 27.2 ng/mL — p=< 0.001
Phase 3 N=436 Vitamin D Supplementation in Cutaneous Malignant Melanoma Outcome
Cutaneous Malignant Melanoma
Primary: Relapse Free Survival — 41; 32 Participants — p== 0.324
Phase 1 N=21 Vitamin D Supplementation in Crohn's Patients
Inflammatory Bowel Disease
Primary: Crohn's Disease Activity Index — 230; 112 units on a scale
Phase 3 N=105 Safety of Vitamin D Supplementation in Older Persons
Vitamin D Deficiency
Primary: Number of Participants Who Develop Hypercalcemia — 0; 2 participants
N/A N=20 Vitamin D Supplementation in Kidney Disease
Renal Dialysis · Vitamin D Deficiency
Primary: Change in Hip Flexor Strength — 20.34; 6.83 percent change
N/A N=33 Vitamin D Supplementation for Bipolar Depression
Bipolar Disorder · Bipolar Depression
Primary: Change in Montgomery-Åsberg Depression Rating Scale — 9.4; 6.4 units on a scale — p=0.89
Phase 2 N=44 Vitamin D Dose Finding Study
HIV Infections · AIDS
Primary: Safety — 0; 0 participants
Phase 3 N=190 Vitamin D Supplementation in HIV Youth
HIV Infections
Primary: Changes in Serum 25(OH)D3 Levels — 11; 22; 7.5; 25 ng/mL
Phase 3 N=1,358 Vitamin D to Improve Outcomes by Leveraging Early Treatment
Acute Respiratory Distress Syndrome · Vitamin D Deficiency · Critical Illness
Primary: All-cause, All-location Mortality to Day 90 — 125; 109 Participants — p=0.26
N/A N=62 Vitamin D Supplements for HIV-positive Patients on cART
HIV-associated Co-morbidities
Primary: 25(OH)D Levels — 13; 20 Participants
N/A N=136 Vitamin D Supplementation and Muscle Function in Older Adults
Neuromuscular Function
Primary: Change in Lower Extremity Muscle Power Over 12 Months — -0.10; -0.13 Watts/kg — p=0.63
Phase 2 N=107 Vitamin D Supplementation and Acute Respiratory Infection in Older Long-Term Care Residents
Respiratory Infection
Primary: Number of Acute Respiratory Infections (ARIs) — 32; 48 events
Phase 4 N=230 Treatment of Vitamin D Insufficiency
Vitamin D Deficiency
Primary: Intestinal Calcium Absorption — 0.200; 0.217; 0.183; 0.206 Total Fractional Calcium Absorption
N/A N=40 Effect of Vitamin D Supplementation on Inflammation and Cardiometabolic Risk Factors in Obese Adolescents
Obesity
Primary: 25OH Vitamin D — 19.6; 25.8; 20.1; 24.6 ng/mL
Phase 2 N=102 Optimal Vitamin D3 Supplementation Strategies for Acute Fracture Healing
Fracture
Primary: Fracture Healing Will be Assessed Clinically Using Function IndeX for Trauma (FIX-IT) — 10.1; 9.7; 9.3; 9.0 scores on a scale
Phase 1 N=157 Defining Vitamin D Insufficiency in School Age Children: A Randomized Placebo Controlled Trial of Vitamin D3
Healthy
Primary: Serum 25-hydroxyvitamin D — 26.7; 22.4 ng/mL — p=0.003
N/A N=112 Vitamin D Oral Replacement in Asthma
Asthma · Vitamin D Deficiency · Pediatric Obesity
Primary: Part 1: Optimal Dosing Level to Use in Part 2 — 8000; 50000 IU
Phase 3 N=62 Improving the Understanding of the Response to Vitamin D Supplementation
Vitamin D Deficiency
Primary: Change in Serum 25-hydroxy Vitamin D3 — 6.0; -0.8; 10.4; 0.3 ng/ml
Phase 1 N=19 Clearance of 25-hydroxyvitamin D3 During Vitamin D3 Supplementation
Chronic Kidney Disease
Primary: Change in Metabolic Clearance of D6-25(OH)D3 — 21; 5 ml/d