N/A N=39 A Novel Approach for Thyroplasty Type 1, With Prolene Mesh. A Prospective Study.
Vocal Cord Paralysis · Phonasthenia · Presbylarynges
Primary: Change in Mean Phonation Time — 7.74; 14.08 seconds
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=30 Evaluating the Feasibility of Acapella® Choice as a Dysphonia Treatment
Muscle Tension Dysphonia · Vocal Fold Palsy · Vocal Cord Paralysis
Primary: Change in Baseline Cepstral/Spectral Index of Dysphonia (CSID) — 1.22; 4.45; 4.56; 3.13 score on a scale
N/A N=42 Laryngeal Vibration for Spasmodic Dysphonia
Spasmodic Dysphonia
Primary: Voice Assessment During First Visit — 0.045; 0.17; 0.13; -0.47 decibel
N/A N=55 Phonatory Movement of the Pharyngoesophageal Mucosa in Laryngectomy Patients
Larynx Cancer · Laryngectomy; Status
Primary: High Speed Video Endoscopy Recordings — 53; 2; 2; 38 Participants
N/A N=30 MyoVoice to Restore Natural, Hands-free Communication to Individuals With Vocal Impairments
Rehabilitation of Speech and Language Disorders · Speech Disorders · Speech, Alaryngeal
Primary: Pitch Recognition Accuracy — 7.70 Percent agreement to reference pitch
N/A N=24 The Effects of Respiratory Training on Voice
Muscle Tension Dysphonia
Primary: Post Training Lung Volume Initiation — 21.07; 27.04 % vital capacity relative to rest level — p=<0.0005
N/A N=125 Intraoperative Video Laryngoscopy as Adjunct for Nerve Monitoring
Vocal Cord Function in Neck Procedures
Primary: Frequency of Congruence of Nerve Integrity and Vocal Cord Functions — 68; 13; 17; 10 nerves at risk
N/A N=6 Thalamic Deep Brain Stimulation for Spasmodic Dysphonia- DEBUSSY Trial
Spasmodic Dysphonia · Laryngeal Dystonia · Deep Brain Stimulation
Primary: Unified Spasmodic Dysphonia Rating Scale (USDRS) — 2.5; 3.75 units on a scale — p=0.025
N/A N=20 Respiratory Muscle Strength Training in Presbyphonia
Presbylarynx
Primary: Post-Treatment Mean in Voice Handicap Index Score — 15.00; 15.75; 18.50 score on a scale — p=0.041
N/A N=100 No Post Intubation Laryngeal Symptoms
Sore-throat · Dysphonia · Dysphagia
Primary: Sore Throat on a Scale From 0 (no Sore Throat) to 10 (Worst Possible Sore Throat) — 1.85; 1.9; 1.1; 1.62 score on a scale — p=0.03
Phase 1 N=20 Bevacizumab for Treatment of Recurrent Respiratory Papillomatosis (RRP)
Recurrent Respiratory Papillomatosis
Primary: The Primary Activity Variable Was the Recurrence of Recurrent Respiratory Papillomatosis (RRP) in Bevacizumab Treated and the Un-treated Vocal Fold in the Same Patient…
N/A N=120 Treatment of Critical Illness Polyneuromyopathy
Acute Respiratory Failure
Primary: The Primary Outcome Variable for This Study Will be the Short Form of the Continuous Scale Physical Functional Performance Test (CS-PFP) Called the PFP-10 — 19.0; 20.9…
N/A N=4 CPAP to Improve Swallow Function Post Total Laryngectomy
Oropharyngeal Dysphagia · Laryngectomy; Status
Primary: Total Pharyngeal Transit Time (With CPAP) — 10.18 seconds — p=<0.05
N/A N=6 Sub-study to Spinal Cord Stimulation to Restore Cough
Spinal Cord Injuries · Spinal Cord Diseases · Paralysis
Primary: The Effects of Electrical Spinal Cord Stimulation (SCS) on Airway Pressure Generation While Using Temporarily Placed Parallel Wire Leads and Implanted Disc Electrodes…
N/A N=11 Efficacy of a Semi-occluded Mask in the Treatment of Patients With Voice Disorders
Voice and Resonance Disorders · Vocal Fold Polyp · Vocal Cord Cyst
Primary: Change From Baseline in VHI-10 Score After 4 Sessions of Voice Therapy — 7 score on a scale — p=.0076
N/A N=54 Electrical Activation of The Diaphragm for Ventilatory Assist
Spinal Cord Injury · Quadriplegia
Primary: Enrolled Subjects Achieve Clinically Acceptable Tidal Volume Sustained Over a Continuous 4 Hour Period. — 52; 1 Participants — p=<0.001
N/A N=31 Controlled Phonation and Vocal Rest Programs After Acute Vocal Exertion in Healthy Adults
Healthy
Primary: Phonation Threshold Pressure — 5.41; 5.08; 6.39; 6.33 cmH20 — p=<0.001
N/A N=6 Diaphragm Pacing in Individuals With Spinal Cord Injuries
Cervical Spinal Cord Injury
Primary: Change in Electromyogram (EMG) — -.0031 mV
Phase 4 N=79 Use of Sugammadex for Reversal of Paralysis in Microlaryngoscopy
Microlaryngoscopy · Rigid Bronchoscopy
Primary: Time to Extubation After End of Procedure — 11.06; 10.36 Minutes
N/A N=36 Voice Treatment for Parkinson's Disease
Idiopathic Parkinson Disease
Primary: Treatment-related Changes in Vocal Intensity Will be Assessed Using Acoustic Analysis. — 3; 3; 0.26 Decibels
Phase 3 N=10 Intratympanic Steroid for Bell's Palsy
Bell's Palsy · Facial Nerve Paresis
Primary: Facial Nerve Recovery — 7; 81.56 Days
Phase 3 N=32 Spasmodic Dysphonia Pain
Spasmodic Dysphonia
Primary: Pain Experienced — 2; 2; 2 score on a scale
Phase 2 N=21 Controlled Study to Evaluate the Safety and Efficacy of Azficel-T for Vocal Fold Scarring and Age-Related Dysphonia
Dysphonia Resulting From Vocal Fold Scarring · Age-related Dysphonia
Primary: Number of Participants With Any Improvement From Baseline in Mucosal Wave Grade — 14; 5 Participants
N/A N=30 Effect of Semi-occluded Vocal Tract Therapy on the Phonation of Children With Vocal Fold Nodules
Voice Disorders in Children · Vocal Nodules in Children · Hoarseness
Primary: Change in Dysphonia Severity Index — 1.8; 1.8; 0.0 units on a scale — p=0.024
Phase 4 N=102 Deep vs Moderate Neuromuscular Blockade With Rocuronium in Patients Undergoing Endolaryngeal Procedures
Laryngoscopic Surgical Procedures
Primary: Proportion of Patients Who Have a Clinically Acceptable Surgical Conditions — 0.89; 1 Proportion of patients
N/A N=20 Early Speech With One-Way Speaking Valve in Tracheostomy Patients
Respiratory Failure · Speech · Aphonia
Primary: Speech Intelligibility as Assessed by Speech Intelligibility Test Score — 25.71; 0 Percentage of intelligible words
N/A N=170 Intubating Conditions of Neuromuscular Blockade
Endotracheal Intubation
Primary: Number of Subjects With Optimal Intubating Conditions — 61; 47 Participants — p=0.036
Phase 4 N=21 Dose-Response Relationships for Hemidiaphragmatic Paresis Following Ultrasound-Guided Supraclavicular Block
Surgery of Right Upper Extremity
Primary: Number of Subjects With Hemidiaphragmatic Paresis at Various Volumes of Local Anesthetic 15 Minutes After Supraclavicular Block — 1; 1; 1; 2 Participants
N/A N=20 rTMS in Spasmodic Dysphonia
Spasmodic Dysphonia · Laryngeal Dystonia
Primary: Adverse Response to rTMS — 0; 0 Participants
Phase 2 N=14 Cough and Swallow Rehab Following Stroke
Ischemic Stroke
Primary: Maximum Expiratory Pressure — 104.31 cm H2O (pressure measurement) — p=.001