Phase 4 N=20 Buspirone Treatment of Anxiety in Williams Syndrome
Williams Syndrome · Anxiety
Primary: Mean 16-Week Change in Pediatric Anxiety Rating Scale 5-Item Total Score — -7.9 score on a scale — p=<0.001
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
Phase 2 N=21 Efficacy of Minoxidil in Children With Williams-Beuren Syndrome
Williams Beuren Syndrome
Primary: Variation of Carotid Intima-media Thickness (IMT) Assessed by Vascular Echography — 0.028; 0.012 mm
N/A N=23 Obstructive Sleep Apnea and Neurocognitive and Cardiovascular Function in Children With Down Syndrome
Down Syndrome · Obstructive Sleep Apnea Syndrome
Primary: Change in Epworth Sleepiness Scale From Baseline to End of Study — -1; -0.5; 1 units on a scale
N/A N=257 Down Syndrome Metabolic Health Study
Down Syndrome · Trisomy 21
Primary: Non-HDL Cholesterol — 128; 107 mg/dl
N/A N=60 Blood Flow Regulation in Individuals With Down Syndrome - Training Study
Down Syndrome
Primary: Change From Baseline Work Capacity at 13 Weeks — -1.20; -0.18 change in ml/kg/min — p=0.660
Phase 2 N=21 A Clinical Trial of Dantrolene Sodium in Pediatric and Adult Patients With Wolfram Syndrome
Wolfram Syndrome · Diabetes Mellitus · Optic Nerve Atrophy
Primary: Number of Participants With Treatment-related Adverse Events as Assessed by Liver Function Tests — 0; 0; 0; 2 Participants
N/A N=27 Retrieval-Based Word Learning in Developmental Language Disorder During Book Reading
Developmental Language Disorder · Specific Language Impairment · Language Development
Primary: Word Form Accuracy (Number of Words Correctly Recalled) in Repeated Spaced Retrieval (RSR) and Repeated Study (RS) Conditions at 5 Mins. — 4.54; 6.5; 1.46; 4.0 number of…
N/A N=28 Retrieval-Based Word Learning in Developmental Language Disorder
Developmental Language Disorder · Specific Language Impairment · Language Development
Primary: Word Form Recall Accuracy (Number of Words Correctly Recalled) on Expanding and Standard Retrieval Schedules at 5 Mins — 3.93; 6.43; 3.71; 5.21 number of words recalled…
Phase 2 N=8 Gene Therapy for Wiskott-Aldrich Syndrome
Wiskott-Aldrich Syndrome (WAS)
Primary: Safety of Reduced Conditioning Regimen — 8 Participants
Phase 2 N=42 Dilated Versus Non-Dilated Wavefront Corrections for Patients With Down Syndrome
Down Syndrome · Refractive Errors
Primary: Distance Visual Acuity — 0.41; 0.41; 0.40; 0.43 logMAR — p=0.92
N/A N=84 Assessing Malleability of Spatial Abilities in Down Syndrome
Down Syndrome
Primary: Change in Mental Rotation Ability at 8 Weeks — 0.0; -0.6; .82 Amount of Change in Number Correct Items — p==.066