N/A N=105 Prevena™ vs Dermabond in Groin Wound Infections in Vascular Surgery
Wound Infection
Primary: Comparison of Healing of Groin Wounds Between Patients Treated With Prevena vs Dermabond — 41; 54 Participants
Clinical Trial Search
Completed trials with posted results — search by concept, filter by the parameters that matter at the bedside.
N/A N=39 Acellular Porcine Dermal Matrix Wound Dressing in the Management of Diabetic Foot Ulcers
Diabetic Foot Ulcers
Primary: Size of Index Wound Based on Calculations Wound Width x Length x Depth 2. Size of Index Wound Based on Calculations Wound Width x Length x Depth — 2.05; 3.33 mm^3
N/A N=30 Procellera and Negative Pressure Therapy for Acute Wounds
Wound
Primary: Wound Infection — 13; 12 participants
N/A N=298 Prevena™ Incisional Negative Pressure Wound Therapy in Re-operative Colorectal Surgery
Surgical Site Infection
Primary: Occurrence of Superficial Surgical Site Infection — 11; 21; 107; 128 Participants
Phase 4 N=15 Healing Ointment Usage Post-surgical Procedure
Surgical Wound
Primary: Objective Erythema Assessment Using Clinical Grading Analog Scale — 0.8; 0.83; 0.75; 0.29 score on a scale
N/A N=104 Treatment of Full-Thickness Wounds: NPWT Combined With Type-I Collagen Based Advanced Skin Substitute Versus NPWT Alone
Full Thickness Skin Defects · Ulcer
Primary: Percentage Change in Wound Area — 23.73; 15.21; 34.47; 22.52 percentage change
Phase 4 N=21 Wound Management for Sacral Pressure Ulcers With Necrotic Tissue
Pressure Ulcers
Primary: Percentage of Wounds Healed — 63.1; 6.1 percentage of wounds
Phase 3 N=244 Assessment of Mechanisms of Improved Wound Healing
Burns
Primary: Decrease Hypermetabolism as Measured by Stable Isotope Infusion Study
Phase 2 N=5 Hidradenitis Suppurativa Wound Care
Hidradenitis Suppurativa (HS)
Primary: Percent Change in Wound Size — 57.2 percentage change in wound size
Phase 3 N=68 Efficacy of the Combination of Isosorbide Dinitrate Spray and Chitosan in Diabetic Foot Ulcers
Diabetic Foot Ulcers
Primary: Biopsies — 2.46; 2.64; 2.56; 2.07 UI/dL
N/A N=8 Topical Collagen Powder for Healing of Acute Full-thickness Wounds
Wound of Skin · Wound Heal
Primary: Change in Wound Diameter — 95.94; 95.94 Centimeters
N/A N=475 Effectiveness of Two Silicone Dressings for Sacral and Heel Pressure Ulcer Prevention
Pressure Ulcer
Primary: Number of Pressure Ulcers Category II, III, IV, Unstageable, Deep Tissue Injury (DTI) at Heels and/or Sacrum (Proportion) — 6; 22 Pressure ulcer
N/A N=1,869 Negative Pressure Wound Therapy for Prevention of Poststernotomy Infection
Surgical Wound Infection
Primary: Wound Infection After Open Heart Surgery — 4; 17 Participants — p=0.55
N/A N=37 Enhanced Secondary Intention Healing vs. Standard Secondary Intention Healing in Mohs Surgical Defects on the Head and Distal Lower Extremities
Wound Heal
Primary: Time to Complete Wound Re-epithelialization on the Head — 41.6; 43 days
Phase 4 N=28 Effect of Collagenase on Healing and Scarring
Scarring · Impaired Wound Healing
Primary: Time to Complete Wound Closure Collagenase Santyl and Vehicle — 12.9; 13.0 Days — p=<0.05
N/A N=272 Evaluation of Closed Incision Negative Pressure Dressing (PREVENA) to Prevent Lower Extremity Amputation Wound Complications
Amputation · Amputation; Postoperative, Sequelae · Wound Dehiscence
Primary: Overall Rate of Wound Complications — 26; 31 Participants
N/A N=515 Use of Platelet-Rich Plasma (PRP) and Platelet-Poor Plasma (PPP) to Prevent Infection and Delayed Wound Healing
Elective Foot and Ankle Surgery.
Primary: Postoperative Infection and Delayed Wound Healing. — 2; 1; 17; 17 participants
Phase 1 N=14 The Effect of OASIS Ultra on Critical Sized Wound Healing
Traumatic Wound · Infective Wound · Iatrogenic Critical Sized Wound Defects
Primary: Change in Wound Size From Baseline to Final Wound Evaluation up to 60 Days Later — -20.7; -13.9 cm^2
Phase 4 N=65 Pressure Ulcer Healing With Microcyn
Pressure Ulcer · Spinal Cord Injuries
Primary: Pressure Ulcer Size (Length x Width x Depth, cm^3) at Baseline — 10.13; 21.00 cm^3
N/A N=41 Developing Strategies for Effective Debridement in Patients for Venous Leg Ulcers
Venous Leg Ulcer
Primary: Change in the Genetic Profile After Debridement in the Intervention Group. — 1031 Number of Differentially Expressed Genes
Phase 2 N=140 Cooling Leg and Foot Ulcer Skin Post Healing to Prevent Ulcer Recurrence
Venous Hypertension Ulcers · Venous Stasis Ulcer · Venous Ulcer
Primary: Number of Participants With Ulcer Recurrence — 6; 3; 11; 5 participants — p=0.091
N/A N=380 The Role of Antimicrobial Foam Dressing in Prevention of Cesarean Section Wound Complications
Cesarean Section; Complications, Wound, Dehiscence
Primary: Number of Participants With Wound Disruption and/or Infection — 5; 9 Participants
N/A N=80 Treatment of Pressure Ulcers Using Biological Skin Substitutes
Pressure Sore
Primary: Percent Change in Wound Area — -78.5; -65.1 percentage change
Phase 1 N=15 Study to Determine if Fibrin Affects the Ability of a Wound to Heal
Effect of Test Articles on the Healing of a Wound Artificially Induced by Liquid Nitrogen Spray
Primary: Time (in Days) to Wound Closure (Healing) Defined as Skin Re-epithelialization, Without Drainage or Dressing Requirements. — 14.4; 13.3 days to wound closure — p=.3393
N/A N=28 Predictive of Biomarkers of Healing in Chronic Venous Ulceration of the Lower Limb
Varicose Ulcer
Primary: Identification of Biomarkers Predictive of Ulcer Healing. — 9 Number of biomarkers
N/A N=200 Nutritional Support in Pressure Ulcer Patients
Pressure Ulcers
Primary: Rate of Healing — 62.9; 43.4 percent change
Phase 2 N=80 Herbal Preparation Used as Adjuvant Therapy on Diabetic Ulcers
Diabetic Foot Ulcer · Amputation
Primary: Number of Participants With Limb Salvage — 37; 31 Participants
N/A N=40 Characterization of AmnioExcel Plus in Two Treatment Paradigms
Diabetic Foot Ulcer
Primary: Number of Participants Who Healed — 6; 10 Participants
N/A N=154 Negative Pressure Wound Therapy to Prevent Wound Complications Following Cesarean Section in High Risk Patients
High Risk Pregnancy · Cesarean Wound Disruption With Postnatal Complication
Primary: Wound Complication — 13; 14 Participants
Phase 3 N=583 Negative Pressure Wound Therapy in Post-Operative Incision Management
Negative-Pressure Wound Therapy
Primary: Number of Post-op Wound Complications — 2; 5; 42; 36 Wound Complications