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Home › Conditions › Nephrolithiasis

Nephrolithiasis

Part of Kidney Diseases

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Nephrolithiasis

18 trials tracked for Nephrolithiasis: 7 in phase 3 or 4 and 1 with published results. The most-cited published study has 125 citations.

18Trials tracked
7Phase 3 & 4
0Recruiting
1With published results
Phase distribution
Phase 4 4 Phase 3 3 Phase 2 3 Other / NA 8
  1. Phase 3 Hydrochlorothiazide for Kidney Stone Recurrence Prevention Completed · 125 cited
  2. Phase 4 A Randomized Trial of Preoperative Prophylactic Antibiotics Prior to Kidney Stone Surgery (Percutaneous Nephrolithotomy [PCNL]) Completed
  3. Phase 4 The Use of Belladonna and Opium Suppository in the Treatment of Postoperative Stent Pain Completed
  4. Phase 4 Narcotic-Free Percutaneous Nephrolithotomy Completed
  5. Phase 4 Vitamin D Repletion in Stone Formers With Hypercalciuria Completed
  6. Phase 3 Perioperative Pregabalin in Ureteroscopy: a Pilot Completed
Show 12 more trials
  1. Phase 3 Pain Outcomes of Non-opioid vs. Opioid Analgesia for Kidney Stone Surgery. Completed
  2. Phase 2 Effect of Antihistamines on Ureteral Stent-Related Symptoms Completed
  3. Phase 2 Use of Oral Probiotics to Reduce Urinary Oxalate Excretion Completed
  4. Phase 2 Evaluating ALLN-177 for Reducing Urinary Oxalate Excretion in Calcium Oxalate Kidney Stone Formers With Hyperoxaluria Completed
  5. N/A Noninvasive Electrical Stimulator as a Pain Control Treatment Post-ureteroscopy Completed
  6. N/A Trial Assessing Renal Damage During Ureteroscopy Completed
  7. N/A Intraoperative Cone-beam CT for Percutaneous Nephrolithotomy Completed
  8. N/A Evaluation of a Nonopioid Recovery Pathway Following Surgery for Kidney Stones Completed
  9. N/A A Pilot Study of Oxalate Absorption in Secondary Hyperoxaluria Completed
  10. N/A A Comparison of Ureteroscopic Treatment of Nephrolithiasis With and Without Moses Technology Completed
  11. N/A Thulium vs. Hol:YAG Laser Completed
  12. N/A Impact Ureteral Sheath Design During Ureteroscopy Completed

Showing the 18 most-cited and recently-updated of 18 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Narrative review discusses renal risks in inflammatory bowel disease patients
Nephrology Sys. Review
Narrative review discusses renal risks in inflammatory bowel disease patients Kidney risks for people with inflammatory bowel disease remain unclear and need more study
This narrative review examines renal complications in individuals with inflammatory bowel disease.
People with inflammatory bowel disease face kidney risks, but current evidence relies on animal studies and lacks human proof.
Frontiers Apr 29, 2026
Extraplanar ultrasound guidance for multi-tract PCNL linked to shorter operative time and hospital stay
Urology Cohort
Extraplanar ultrasound guidance for multi-tract PCNL linked to shorter operative time and hospital stay Could a different ultrasound angle make kidney stone surgery easier?
A retrospective cohort study of 91 patients with complex renal stones compared extraplanar to conventional ultrasound guidance for multi-tra…
A different ultrasound angle for kidney stone surgery linked to shorter operations, quicker hospital stays, and better kidney function after…
Frontiers Apr 3, 2026
CVAC Aspiration System achieves 96% stone clearance in small renal stone evacuation study
Urology
CVAC Aspiration System achieves 96% stone clearance in small renal stone evacuation study New kidney stone removal system shows high clearance rate in small study
A prospective single-arm study of 30 subjects with renal stones evaluated the second-generation CVAC Aspiration System for ureteroscopic eva…
A new kidney stone removal device cleared 96% of stone volume in a small study, though only 46% of patients had zero fragments left.
Apr 2, 2026

Questions about Nephrolithiasis

What renal complications might occur in patients with inflammatory bowel disease?

Patients with inflammatory bowel disease face specific kidney risks including chronic kidney disease, glomerulonephritis, and nephrolithiasis, with some stones directly linked to medications like mesalazine.

Full answer →
Do people with inflammatory bowel disease have higher risks of kidney stones?

People with inflammatory bowel disease, especially Crohn's disease, have a higher risk of kidney stones due to malabsorption and chronic inflammation.

Full answer →