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Intraoperative ESP block yields higher postoperative recovery scores than preoperative block in lumbar disk hernioplastyWhen should you get a nerve block for back surgery? Timing might affect how you feel afterward

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Key Takeaway
Consider that intraoperative ESP block timing may offer a marginal recovery benefit over preoperative timing in lumbar surgery.

This single-blind randomized controlled trial enrolled 100 adults (ASA I-III) undergoing elective single-level lumbar disk hernioplasty. Patients were randomized to receive an erector spinae plane block either before anesthesia induction (preoperative) or after induction (intraoperative). The primary outcome was not explicitly stated, but secondary outcomes included Quality of Recovery-40 (QoR-40) and State-Trait Anxiety Inventory (STAI) scores.

The main finding was a statistically significant difference in the total QoR-40 score, favoring the intraoperative block group (P = .02). However, the authors determined this difference reached only the threshold for minimal clinical significance. The intraoperative block group also had a significantly higher score on the QoR-40 emotional status subparameter. No significant differences were found between groups for other QoR-40 subdimensions (physical comfort, independence, support, pain) or for postoperative anxiety (STAI-1) scores.

Safety and tolerability data were not reported. Key limitations include the single-blind design, a modest sample size of 100, and the lack of a reported primary outcome. The absence of safety data and details on follow-up duration are notable gaps. For practice, this evidence suggests the procedural timing of an ESP block may have a small, statistically detectable effect on patient-reported recovery quality, particularly emotional status, in this specific surgical context, but the clinical relevance of this difference is uncertain.

If you're facing back surgery, you might wonder about the little details that could make recovery smoother. A new study looked at one of those details: when to give a common nerve-blocking injection called an erector spinae plane (ESP) block. The researchers compared giving it before anesthesia, while the patient is awake, versus after anesthesia, while the patient is asleep.

The study involved 100 adults having surgery for a herniated disk in their lower back. The main finding was that patients who got the block after being put to sleep reported slightly higher overall recovery scores 24 hours later. This difference was statistically significant, meaning it's unlikely to be due to chance. The improvement was mostly in how patients felt emotionally, not in their physical comfort, pain, or ability to move around. Importantly, the study authors noted this difference was 'minimally clinically significant,' meaning patients might not notice a major real-world change.

Notably, the timing of the block didn't make a difference in patients' anxiety levels before or after surgery. The study was relatively small and 'single-blind,' meaning only the patients didn't know which timing they received, which can sometimes influence results. The researchers didn't report on safety or side effects. This gives us an early clue that timing might matter for how a patient feels, but it's not yet a strong reason to change standard practice.

What this means for you:
For back surgery, getting a nerve block after you're asleep might help your mood slightly more than getting it while awake.

Study Details

Study typeRct
Sample sizen = 100
EvidenceLevel 2
Follow-up780.0 mo
PublishedApr 2026
View Original Abstract ↓
PURPOSE: The aim of this study is to compare the effects of preoperatively administered erector spinae plane (ESP) block, applied either before or after anesthesia induction, on recovery quality, anxiety, and patient satisfaction in patients undergoing elective lumbar disk hernioplasty. DESIGN: Prospective, randomized, controlled, single blind study. METHODS: This study involved 100 patients aged 18 to 65 years with American Society of Anesthesiologists physical status I to III who underwent elective single-level lumbar disk hernioplasty. Participants were allocated into two groups: the group receiving the block after anesthesia induction (intraoperative) was named group I, and the group receiving the block before anesthesia induction (preoperative) was named group P. Preoperative demographic data were gathered for all patients, and State-Trait Anxiety Inventory (STAI-I and STAI-II) questionnaires for evaluating anxiety, as well as Quality of Recovery-40 (QoR-40) questionnaires for assessing postoperative recovery, were administered. FINDINGS: Postoperative QoR-40 data were significantly higher in group I compared with group P (P = .02). However, the minimal clinically important difference was determined to be minimally clinically significant. One of the subparameters of the QoR-40 score, emotional status scores, was found to be statistically significantly higher in group I. However, no significant differences were found between preoperative and postoperative physical comfort, physical independence, patient support, and pain subdimensions (P > .05). No difference was observed between the groups in postoperative STAI-1 scores and in the change in STAI-1 scores from preoperative to postoperative (P > .05). CONCLUSIONS: Although the recovery quality of patients who received ESP block after anesthesia induction was statistically significant compared with those who received ESP block before anesthesia induction, it was not clinically significant. Our findings showed that differences in the timing of ESP block application did not change the results.
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