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Acupuncture plus usual care did not improve acute musculoskeletal pain at 1 month

Acupuncture plus usual care did not improve acute musculoskeletal pain at 1 month
Photo by Gary Meulemans / Unsplash
Key Takeaway
Interpret the primary result as no benefit of acupuncture for acute musculoskeletal pain; exploratory findings require confirmation.

This pragmatic randomized trial enrolled 599 adults with acute (≤7 days) musculoskeletal pain in the neck, back, and/or extremities. Patients were randomized to acupuncture plus usual care or usual care alone. The primary outcome was pain score at 1 month.

At 1 month, pain scores were similar between groups: control 3.8 (SD 3.2) and acupuncture 3.2 (SD 3.0). The difference was not statistically significant (p-value not reported). In an exploratory analysis, patients who attended 6 or more acupuncture sessions (20.2% of the acupuncture group) experienced significant pain improvements compared to those with fewer sessions.

Safety and adverse events were not reported. Notably, 178 patients (43.4%) in the acupuncture arm were unable to attend clinic due to time and financial constraints, leading to high dropout. This limits the interpretability of the exploratory findings.

Key limitations include high dropout in the acupuncture arm and the exploratory nature of the subgroup analysis. The primary analysis showed no benefit, and the exploratory finding is association only, not causation. Improving access to acupuncture may be needed for effective pain management, but current evidence does not support routine use for acute musculoskeletal pain.

Study Details

Study typeRct
EvidenceLevel 2
PublishedMay 2026
View Original Abstract ↓
BACKGROUND: cute musculoskeletal pain in emergency department (ED) patients is challenging to treat with medications alone, but adding acupuncture may improve pain outcomes. METHODS: In this pragmatic randomized controlled trial, acupuncture was delivered by licensed acupuncturists in the ED and twice a week in follow-up clinic for 1 month. From February 10, 2020 to April 19, 2023, 2781 adult patients at an academic ED with acute (≤7 days) musculoskeletal pain in neck, back and/or extremities were screened, and 599 were enrolled and randomized to usual care only (n = 189, 31.6%) or acupuncture plus usual care (n = 410, 68.4%). RESULTS: Acupuncture and control arms had similar demographics (mean age 45.2, SD 15.8; 57.7% female) and baseline pain scores (control 7.1, SD 2.2; acupuncture 7.1, SD 2.3). At 1 month, pain scores were similar between arms (control 3.8, SD 3.2; acupuncture 3.2, SD 3.0). However, 178 (43.4%) participants in the acupuncture arm were unable to attend acupuncture clinic and reported time and financial constraints. Exploratory analysis of pain score by number of clinic sessions attended showed that patients attending 6 or more acupuncture sessions (n = 121, 20.2%) experienced significant pain improvements compared to those with fewer sessions (n = 478, 79.8%). CONCLUSION: Improving access and availability of acupuncture in outpatient settings may be needed for more effective pain management.
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