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Can parechovirus A cause pharyngitis and tonsillitis in hospitalized children?

high confidence  ·  Last reviewed May 27, 2026

Parechovirus A (PeV-A) is a virus that can cause respiratory infections in children. While it is often found alongside other viruses, research shows that when PeV-A is the only virus detected, it is strongly linked to upper respiratory tract infections, particularly pharyngitis (sore throat) and tonsillitis (inflamed tonsils). In hospitalized children, single PeV-A infections were a likely cause of these conditions in most cases.

What the research says

A study of children hospitalized with respiratory tract infections found that 4.6% had PeV-A as the only virus detected 36. Among these children with single PeV-A, medical records showed that PeV-A was a likely cause of pharyngitis and tonsillitis in 10 out of 15 cases 36. The same study also looked at children in day-care settings and found that 8 out of 10 with single PeV-A had pharyngitis and tonsillitis 36. Statistical analysis confirmed a strong association between single PeV-A and upper respiratory tract infections (like pharyngitis) compared to lower respiratory tract infections (like pneumonia) 36. However, when PeV-A was found together with other viruses like RSV or rhinovirus, it did not seem to affect the severity or type of illness 36. Other sources on respiratory infections in children do not specifically address PeV-A 1245.

What to ask your doctor

  • Could my child's pharyngitis or tonsillitis be caused by parechovirus A?
  • Is testing for parechovirus A available and recommended for hospitalized children with sore throat?
  • How does treatment differ if parechovirus A is the cause versus other viruses?
  • What should I watch for if my child has a parechovirus A infection?

This question is drawn from common patient questions about this topic and answered using cited medical research. We do not provide individualized advice.