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Respiratory Tract Infections

Subtypes of Respiratory Tract Infections

Respiratory Viral Infections 5 Lower Respiratory Tract Infection 4 Acute Respiratory Illness 2

15 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Respiratory Tract Infections

33 trials tracked for Respiratory Tract Infections: 8 in phase 3 or 4 and 5 with published results. The most-cited published study has 192 citations.

33Trials tracked
8Phase 3 & 4
0Recruiting
5With published results
Phase distribution
Phase 4 2 Phase 3 6 Phase 2 7 Other / NA 18
  1. Phase 3 Efficacy, Safety, and Immunogenicity of a Plant-Derived Quadrivalent Virus-Like Particles (VLPs) Influenza Vaccine in Adults Completed · 192 cited
  2. Phase 3 Efficacy of a Plant-derived Quadrivalent Virus-like Particle (VLP) Vaccine in the Elderly Completed · 192 cited
  3. Phase 3 A Trial to Evaluate the Efficacy and Safety of RSVpreF in Infants Born to Women Vaccinated During Pregnancy. Completed · 78 cited
  4. Phase 3 Lot-to-lot Consistency of a Plant-Derived Quadrivalent Virus-Like Particles Influenza Vaccine in Healthy Adults Completed · 72 cited
  5. Phase 3 Efficacy of Antibiotics in Children With Acute Sinusitis: Which Subgroups Benefit? Completed · 40 cited
  6. Phase 4 Study to Evaluate the Safety and Clinical Efficacy of Augmentin® Extra Strength-600 in Children With Acute Otitis Media in India Completed
Show 27 more trials
  1. Phase 4 Individualizing Treatment for Asthma in Primary Care Completed
  2. Phase 3 A Phase 3 Study to Determine if RTB101 Prevents Clinically Symptomatic Respiratory Illness in the Elderly Completed
  3. Phase 2 A PHASE 2B PLACEBO-CONTROLLED, RANDOMIZED STUDY OF A RESPIRATORY SYNCYTIAL VIRUS (RSV) VACCINE IN PREGNANT WOMEN Completed
  4. Phase 2 A STUDY OF A RSV VACCINE WHEN GIVEN TOGETHER WITH TDAP IN HEALTHY NONPREGNANT WOMEN AGED BETWEEN 18 TO 49 YEARS Completed
  5. Phase 2 A Study to Describe the Safety and Immunogenicity of a RSV Vaccine in Healthy Adults Completed
  6. Phase 2 Daily Vitamin D for Sickle-cell Respiratory Complications Completed
  7. Phase 2 A Study to Evaluate Safety and Immunogenicity of One or Two Booster Vaccinations With H5N6 Influenza Vaccine in Adults Primed With H5N1 Influenza Vaccine or Unprimed Completed
  8. Phase 2 A Study to Evaluate the Safety, Tolerability and Immunogenicity of an Investigational RSV Vaccine Candidate (Ad26.RSV.preF) in Adults 18 to 50 Years of Age, and RSV-seropositive Toddlers 12 to 24 Months of Age Completed
  9. Phase 2 Safety, Tolerability, and Pharmacokinetics of Clesrovimab (MK-1654) in Infants (MK-1654-002) Completed
  10. N/A Novel Mucosal Correlates Of RSV Protection In Older Adults Completed
  11. N/A Patient Portal Flu Vaccine Reminders (5) Completed
  12. N/A Compliance And Safety Study In Children With Upper And Lower Respiratory Tract Infections Completed
  13. N/A Patient Portal Flu Vaccine Reminders_RCT 5 (LADHS) Completed
  14. N/A Measuring the Influence of Kefir on Children's Stools on Antibiotics (MILK) Completed
  15. N/A Home Usability of a Nasal Lavage System in Children Completed
  16. N/A Study on Cefotaxime and Sulbactam Sodium for Injection (2:1) for Treatment of Respiratory and Urinary Tract Infection Completed
  17. N/A Patient Portal Reminder/Recall for Influenza Vaccination in a Health System- UCLA Portal R/R Influenza RCT 3 Completed
  18. N/A Evaluation of the Treatment With Klacid SR in Patients With Acute Tracheitis, Tracheobronchitis and Bronchitis, Acute Exacerbation of Chronic Bronchitis and Mild Community-acquired Pneumonia in Common Clinical Practice in Ukraine Completed
  19. N/A Improving Antimicrobial-Prescribing in Emergency Departments Completed
  20. N/A Recovery Time in Thai Patients With Upper or Lower Respiratory Tract Infections Treated With Klacid MR Completed
  21. N/A Patient Portal - Flu Reminder Recall Completed
  22. N/A Patient Portal Flu Vaccine Reminders (RCT 6) Completed
  23. N/A Rapid Diagnostics for Upper Respiratory Infections in the Emergency Department Completed
  24. N/A Clarithromycin Modified Release Observational Study for Evaluation of Treatment, Tolerability & Recovery Time in Saudi & Egyptian Clinical Settings (CLOSER) Completed
  25. N/A Probiotics and Infections in Conscripts in Military Service Completed
  26. N/A Patient Portal Reminder/Recall for Influenza Vaccination in a Health System- RCT 2 Completed
  27. N/A Acute Safety and Acceptability Study of Experimental Device RD19 for Protection From Human Respiratory Disease Pathogens Completed

Showing the 33 most-cited and recently-updated of 33 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Questions about Respiratory Tract Infections

Which group of children had the highest burden of respiratory tract infections after COVID restrictions lifted?

Preschoolers (4–6 years) had the highest burden of respiratory tract infections after COVID restrictions lifted, with a 68.3% pathogen detection rate.

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Can parechovirus A cause pharyngitis and tonsillitis in hospitalized children?

Yes, parechovirus A can cause pharyngitis and tonsillitis in hospitalized children, especially when detected alone without other viruses.

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Are frequent snacks linked to more frequent respiratory tract infections in preschoolers?

Frequent snacks are linked to a higher risk of recurrent respiratory tract infections in preschoolers, according to a meta-analysis of global studies.

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Can passive smoking increase the risk of recurrent respiratory tract infections in young children?

Yes, passive smoking is a significant risk factor that increases the likelihood of recurrent respiratory tract infections in young children.

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Does having asthma make a preschooler more likely to get a respiratory tract infection?

Yes, asthma significantly increases a preschooler's risk of recurrent respiratory tract infections, with meta-analysis showing about 3 times higher odds.

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See all 5 questions about Respiratory Tract Infections →

All Respiratory Tract Infections Articles