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In-hospital mortality rates for coronary artery disease patients following PCI remain within international benchmarksPCI mortality rates in Asia-Pacific region within international benchmarks

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Key Takeaway
Note that in-hospital mortality rates for coronary artery disease following PCI are consistent with international benchmarks.

This meta-analysis synthesizes data from 27 studies encompassing 16 unique registries involving patients with coronary artery disease undergoing percutaneous coronary intervention (PCI) in the Asia-Pacific region. The analysis focuses on clinical outcomes including in-hospital mortality and ST-elevation myocardial infarction prevalence.

The primary finding indicates that in-hospital mortality rates ranged from 0.26% to 2.80%, with most registries reporting rates between 0.9% and 1.6%. Additionally, the prevalence of ST-elevation myocardial infarction was reported between 6.8% and 58.7%. These results suggest that outcomes in this region align with international benchmarks.

Several limitations are noted, including significant methodological diversity which limits direct regional comparisons. The authors also highlight heterogeneity in dataset structure, variable definitions, and data management approaches across the included studies. Because these findings are derived from observational registry data rather than primary clinical trials, results should be interpreted as associations only.

For clinical practice, the study suggests that standardized dataset requirements are necessary to improve data harmonization. While mortality rates were consistent with global expectations, the diversity in reporting highlights a need for more uniform data collection protocols in regional registries.

How this fits prior evidence

This meta-analysis addresses gaps in regional data consistency by synthesizing 27 studies from 16 different registries. The finding that in-hospital mortality rates are between 0.26% and 2.80% (with most at 0.9% to 1.6%) provides a baseline for regional outcomes. This complements existing evidence regarding CAD management, such as the use of heart team decision making for complex cases or the role of PIV as a risk marker in ACS patients undergoing PCI.

A new meta-analysis of 27 studies covering 16 registries in the Asia-Pacific region looked at how many people with coronary artery disease died in the hospital after having a procedure called percutaneous coronary intervention (PCI), also known as angioplasty with stenting. The analysis included data from thousands of patients across the region.

The study found that in-hospital death rates ranged from 0.26% to 2.80%, with most registries reporting rates around 0.9% to 1.6%. These numbers are similar to what has been seen in other parts of the world. The researchers also noted that the percentage of patients having a severe heart attack (ST-elevation myocardial infarction) varied widely, from 6.8% to 58.7%.

Because this was a meta-analysis of registry data, it can only show associations, not cause and effect. The main limitation was that the registries used different methods to collect and define their data, which made it hard to compare results directly across the region.

What this means for patients is that PCI appears to be a safe procedure in the Asia-Pacific region, with death rates in line with international standards. However, the study highlights the need for more uniform data collection to better understand and improve heart care across different countries.

What this means for you:
PCI in-hospital death rates in Asia-Pacific are low and similar to global benchmarks, but data differences limit comparisons.

Common questions

What is PCI?

PCI stands for percutaneous coronary intervention, also known as angioplasty with stenting. It is a procedure to open blocked arteries in the heart to improve blood flow.

What was the in-hospital death rate after PCI in this study?

The in-hospital death rate ranged from 0.26% to 2.80% across registries, with most reporting rates around 0.9% to 1.6%.

How does this compare to other regions?

The study found that these mortality rates are within international benchmarks, meaning they are similar to what is seen in other parts of the world.

What were the main limitations of this study?

The main limitations were that the registries used different methods to define and collect data, making it hard to compare results directly across the region.

Study Details

Study typeMeta analysis
EvidenceLevel 1
PublishedJul 2026
View Original Abstract ↓
BACKGROUND: Percutaneous coronary intervention registries are pivotal for monitoring cardiovascular care. While several registries exist across the Asia-Pacific region, methodological diversity limits regional comparison. This systematic review aimed to summarize methodological characteristics, patient profiles, and in-hospital mortality rates in Asia-Pacific percutaneous coronary intervention registries. METHODS: A systematic literature search was conducted across MEDLINE, Embase, Scopus, Web of Science, and ProQuest Central, up to June 2025. Data on registry design, dataset characteristics, patient demographics, cardiovascular risk factors, procedural details, and in-hospital outcomes were extracted and synthesized qualitatively, with in-hospital mortality rates pooled using a random-effects model. RESULTS: A total of 27 studies encompassing 16 unique registries from nine countries were included. Despite targeting similar populations of patients with coronary artery disease undergoing intervention, marked heterogeneity existed in dataset structure, variable definitions, and data management approaches. Across all registries, men predominated, and hypertension and dyslipidemia were the most prevalent cardiovascular risk factors. The proportion of patients presenting with ST-elevation myocardial infarction ranged from 6.8% to 58.7%. In-hospital mortality rates ranged from 0.26% to 2.80%, with most registries reporting rates around 0.9-1.6%. CONCLUSIONS: The Asia-Pacific region would benefit from unified dataset standards to enhance data harmonization and comparability. While in-hospital mortality rates varied, they generally fell within international benchmarks, suggesting effective acute management. Further longitudinal data are needed to evaluate long-term outcomes and the broader impact of registry-based monitoring on enhancing quality in cardiovascular care.
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