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Geographic and socioeconomic disparities limit access to mechanical circulatory support and heart transplantationHeart Devices and Transplants Are Out of Reach for Many

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Key Takeaway
Recognize that 90% of heart transplants occur in North America and Western Europe, highlighting significant global inequities.

This narrative review with scoping methods explores the global distribution and accessibility of mechanical circulatory support (MCS) and heart transplantation for patients with advanced heart failure and cardiogenic shock. The review focuses on the systemic barriers to equitable access rather than clinical trial outcomes.

The authors synthesize data indicating significant geographic concentration of procedures. Approximately 90% of heart transplantation procedures were performed in North America and Western Europe. Furthermore, the availability of temporary MCS is largely limited to tertiary care centers, while durable left ventricular assist device (LVAD) availability is concentrated in high-income settings.

The review identifies infrastructure, workforce, and regulatory factors as primary barriers to equitable access. The authors propose a practical implementation roadmap to address these systemic hurdles. These findings suggest that while these interventions are clinically available, their distribution is heavily influenced by regional resources and socioeconomic factors.

How this fits prior evidence

This review addresses a gap in the understanding of systemic barriers to advanced heart failure treatments. While prior coverage noted that conduction system pacing can reduce heart failure hospitalization and that culturally tailored meal programs can reduce hospitalization rates, this review focuses on the structural and geographic inequities in providing mechanical circulatory support and heart transplantation.

If you have advanced heart failure and live in the wrong part of the world, getting a heart transplant or a mechanical heart pump may not be an option at all. A new review looked at how these life-supporting treatments are distributed globally and found a stark gap. Historically, about 90% of heart transplants happened in North America and Western Europe. Temporary mechanical support was mostly available only at major specialty centers, and durable heart pumps were concentrated in high-income countries. The review points to systemic barriers like infrastructure, workforce, and regulation, not differences in how well the treatments work. It does not report patient numbers, safety data, or follow-up results. The authors propose a practical roadmap to improve fair access, but the review itself is a description of the problem, not a test of solutions. For patients, the takeaway is simple: where you live can shape whether you get these options, and the gap is wide.

What this means for you:
Heart transplants and pumps are concentrated in wealthy regions, leaving many patients without access.

Common questions

What did the review find about heart transplant access?

The review found that historically about 90% of heart transplants were performed in North America and Western Europe. That means patients in many other parts of the world had far less access to this treatment.

Where are mechanical heart pumps available?

Temporary mechanical support was largely limited to tertiary care centers, and durable heart pumps were concentrated in high-income settings. So even within a country, access can depend on whether you live near a major specialty hospital.

Does the review say these treatments are unsafe?

No. The review did not report safety data, side effects, or how well the treatments worked. It focused on where these treatments are available and the barriers that keep them from reaching more people.

What can be done to improve access?

The review proposes a practical implementation roadmap to address barriers like infrastructure, workforce, and regulation. It does not test whether the roadmap works, so it is a starting point for discussion, not a proven solution.

Study Details

Study typeSystematic review
EvidenceLevel 1
PublishedSep 2026
View Original Abstract ↓
Mechanical circulatory support (MCS) and heart transplantation are established therapies for advanced heart failure and cardiogenic shock. Technological advances have improved outcomes, including randomized evidence supporting the use of temporary MCS, such as percutaneous ventricular assist devices, in selected patients with ST-elevation myocardial infarction–related cardiogenic shock, alongside substantial gains in survival with contemporary durable left ventricular assist devices (LVADs). Despite this progress, access remains highly inequitable. Although global transplant activity has increased in recent years, heart transplantation remains concentrated in a small number of regions; historically, approximately 90% of procedures have been performed in North America and Western Europe. Similarly, temporary MCS use is largely limited to tertiary care centers, while durable LVAD use is concentrated in high-income settings. These disparities reflect differences in health system capacity across infrastructure, workforce, regulation, financing, culture, ethics, longitudinal follow-up, and data systems, as well as variation in health-system investment, language access, health literacy, and the completeness of registry-based data capture. In many resource-limited settings, fragmented care pathways lead to a “bridge to nowhere,” where temporary support is initiated without access to definitive therapy. In this narrative review with scoping methods, we examine global variation in access to MCS and heart transplantation, map patient care pathways, and organize barriers into key system domains. We further synthesize potential solutions and propose a practical implementation roadmap spanning regionalized shock systems, durable MCS referral and follow-up networks, donor management infrastructure, workforce development, health financing strategies, and registry-based quality improvement.
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