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Laparoscopic gastrojejunostomy resolved symptoms in a patient with superior mesenteric artery syndrome and duodenal strictureMan Vomits After Meals For 30 Years — Then Surgeons Find Two Hidden Problems

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Key Takeaway
Consider laparoscopic bypass for fixed fibrotic strictures after conservative therapy fails, but await larger series for long-term efficacy data.

This case report and literature review details the management of a 40-year-old man diagnosed with superior mesenteric artery syndrome, duodenal bulb–descending ulcerative stricture, and duodenal stasis syndrome. The patient initially underwent long-term conservative therapy, which failed to resolve his condition. Consequently, he underwent a laparoscopic side-to-side gastrojejunostomy with Braun anastomosis. The study notes that superior mesenteric artery syndrome and ulcer-induced strictures may create a dual-level obstruction forming a vicious cycle, necessitating intervention when conservative measures fail.

At the one-year follow-up, the patient achieved complete symptom resolution. Additionally, favorable weight recovery was observed. The report does not provide specific absolute numbers for weight change or statistical measures for these outcomes, as this is a single-patient case. No adverse events, serious adverse events, discontinuations, or specific tolerability data were reported in this instance.

Key limitations of this evidence include the small sample size of one patient and the lack of comparative data against other surgical techniques. The authors state that further evidence from larger clinical series is required to confirm long-term efficacy. Therapeutic strategies for these conditions remain debated among conservative, endoscopic, and surgical approaches. However, this case suggests that minimally invasive bypass surgery may offer more durable outcomes in patients with fixed fibrotic strictures where conservative management has failed.

A pain that never made sense

Duodenal stasis is a long name for a simple problem. Food gets stuck near the top of the small intestine and cannot move forward.

That stuck food causes bloating, nausea, and vomiting after meals. Over time, people lose weight, feel weak, and start to fear eating.

Most cases come from one of two causes. Either the muscles fail to push food along, or something physically blocks the path.

Why doctors often miss it

One known cause is called superior mesenteric artery syndrome, or SMAS. In SMAS, a major blood vessel presses on the small intestine like a clamp.

Another cause is scarring from old ulcers, which can shrink the intestine into a narrow tunnel. Both are uncommon. Having both at the same time is even rarer.

That mix is what stumped this patient's doctors for decades.

The old way of thinking

For years, doctors usually looked for one cause and treated that. If they found ulcers, they treated ulcers. If they found SMAS, they tried weight gain or feeding tubes to relax the artery's grip.

But here's the twist. When two problems team up, fixing only one leaves the patient just as sick.

That is what kept happening to this man. His treatments helped a little, then the symptoms came roaring back.

A traffic jam with two roadblocks

Think of the small intestine as a one-lane highway. Food is the traffic.

In this patient, scarring from ulcers had built a wall halfway down the road. Just past that wall, the artery above was pressing the road flat, like a heavy boot stepping on a garden hose.

Even if you cleared the wall, the boot was still there. Even if you lifted the boot, the wall remained.

This is why one treatment alone could never fix him.

The team used two tools to see the full picture. A camera scope looked inside the gut and found the ulcer scars. A special CT scan with dye showed the artery squeezing the intestine from the outside.

Once they saw both problems, they chose a keyhole surgery called a laparoscopic gastrojejunostomy with a Braun anastomosis. In plain English, surgeons built a new path that lets food skip past both blockages.

It is like adding a bypass road around a permanently jammed intersection.

The result that stunned the team

After surgery, the man's symptoms vanished. No more vomiting. No more painful bloating after meals.

One year later, he had gained healthy weight and was eating normally. For someone who had suffered for 30 years, that change is hard to put into words.

But there is a catch.

One patient is not proof

This is a single case report. That means doctors are sharing one person's story to help other doctors learn.

It does not prove the surgery will work for everyone with similar problems. It does, however, show what is possible when teams look harder for hidden second causes.

Where this fits in the bigger picture

Many specialists already know about SMAS and ulcer scars on their own. What this case adds is the reminder that the two can stack on top of each other.

When standard treatments fail and symptoms keep returning, doctors may need to look for more than one problem at the same time. Combining a scope with a CT angiogram can reveal what either test alone might miss.

If you or a loved one has had years of unexplained vomiting, bloating, or weight loss after eating, this report is worth knowing about. It does not mean you have SMAS or ulcer scars.

But it does suggest that asking your doctor about advanced imaging, like a CT angiogram, may be reasonable when answers are not coming. Keyhole bypass surgery is already available in many hospitals for people with fixed, scarred blockages.

Honest limits

This story is one patient, treated at one hospital, by one team. There was no comparison group and no long-term tracking beyond a year.

Larger studies are still needed to know how often this double-blockage pattern happens and how well bypass surgery works over many years.

Researchers hope future case series will gather more patients with similar mixed blockages. That data could help build clearer guidelines for when to choose surgery over diet, medicines, or stents.

For now, this case is a valuable nudge to the medical world. When a patient has suffered for decades without answers, the right next step may be looking twice — and looking deeper.

Study Details

Study typeSystematic review
EvidenceLevel 1
PublishedApr 2026
View Original Abstract ↓
Duodenal stasis syndrome is a clinical condition characterized by impaired emptying of the proximal duodenum, arising from either functional motility disorders or mechanical obstruction. Superior mesenteric artery syndrome (SMAS) is the most recognized mechanical cause; however, its coexistence with ulcer-related duodenal strictures is rare and presents considerable diagnostic and therapeutic challenges. A 40-year-old man presented with recurrent postprandial epigastric distension and vomiting for more than 30 years. Endoscopy revealed complex ulcers with stenosis involving the duodenal bulb and descending segment, and CT angiography demonstrated markedly reduced aortomesenteric angle (AMA) and distance (AMD), consistent with SMAS. Given the failure of long-term conservative therapy, laparoscopic side-to-side gastrojejunostomy with Braun anastomosis was performed, resulting in complete symptom resolution and favorable weight recovery at one-year follow-up. This case illustrates how SMAS and ulcer-induced strictures may create a dual-level obstruction forming a vicious cycle, and emphasizes the need for integrated evaluation using CT angiography and high-resolution endoscopy. Therapeutic strategies remain debated among conservative, endoscopic, and surgical approaches, whereas minimally invasive bypass surgery offers more durable outcomes in patients with fixed fibrotic strictures. Clinicians should maintain a high index of suspicion for SMAS and associated lesions in patients with long-standing upper gastrointestinal obstruction. Complementary assessment using CT angiography and endoscopy is essential for identifying complex obstructive mechanisms. In selected patients with combined vascular compression and fixed duodenal stenosis, laparoscopic bypass reconstruction may represent an effective therapeutic option, although further evidence from larger clinical series is required to confirm its long-term efficacy.
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