In adult aortic regurgitation surgery, LVEF 55–60% with enlargement linked to higher readmission risk.

This single-center retrospective cohort study evaluated 841 adult patients diagnosed with aortic regurgitation who underwent surgical treatment. The primary exposure was defined as a left ventricular ejection fraction (LVEF) of 55–60% with concomitant left ventricular enlargement. The main outcome assessed was the risk of unplanned readmission during postoperative follow-up, though the specific duration of this follow-up was not reported in the data provided.

Patients in the LVEF 55–60% group with left ventricular enlargement experienced a significantly higher risk of postoperative unplanned readmission. The hazard ratio was 4.118, with 95% CI: 1.488–11.397; P = 0.006. In absolute terms, 46 patients experienced unplanned readmission within the study cohort. No specific adverse events, serious adverse events, discontinuations, or tolerability data were reported for the intervention or comparator groups.

Key limitations include the single-center setting, the retrospective nature of the study, and the fact that the comparator group was not reported. Causality cannot be inferred from this observational design. The study does not provide data on safety profiles or specific adverse event rates. Consequently, the clinical relevance of these findings requires cautious interpretation before altering practice patterns.