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Aortic regurgitation

Part of Aortic Valve Disease

3 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for aortic regurgitation

3 trials tracked for aortic regurgitation.

3Trials tracked
0Phase 3 & 4
0Recruiting
0With published results
  1. N/A China S3: Safety and Effectiveness of Edwards Lifesciences SAPIEN 3 THV in the Chinese Population Completed
  2. N/A HAART Model 300 Annuloplasty Ring Completed
  3. N/A China XT: Safety and Effectiveness of Edwards Lifesciences SAPIEN XT THV in the Chinese Population Completed

Showing the 3 most-cited and recently-updated of 3 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.

Research across Aortic Valve Disease

Related studies from across the Aortic Valve Disease family.

Dapagliflozin associated with lower risk of heart failure in frail patients with aortic stenosis
Cardiology RCT
Dapagliflozin associated with lower risk of heart failure in frail patients with aortic stenosis Trial shows dapagliflozin may help frail patients with aortic stenosis
This post hoc analysis examined the impact of dapagliflozin on patients with severe aortic stenosis undergoing transcatheter aortic valve im…
A new analysis suggests the medication dapagliflozin may offer specific benefits for patients with aortic stenosis who are also experiencing…
Mechanical Aortic Valves Carry Persistent Complication Burden Over 7.1 Years
Orthopedics & Sports Medicine Meta-analysis
Mechanical Aortic Valves Carry Persistent Complication Burden Over 7.1 Years Data Shows Long-Term Risks for Mechanical Aortic Valve Patients
This meta-analysis of 32 studies (24,960 patients) characterizes the long-term burden of valve-related complications after mechanical aortic…
New data tracks the long-term risks of bleeding and blood clots for patients with mechanical aortic valve replacements over several years.
TAV-in-TAV shows lower mean transvalvular gradients than TAV-in-SAV in aortic stenosis reinterventions
Cardiology Meta-analysis
TAV-in-TAV shows lower mean transvalvular gradients than TAV-in-SAV in aortic stenosis reinterventions TAV-in-TAV shows lower pressure gradients in aortic stenosis patients
This meta-analysis of observational studies compared TAV-in-TAV and TAV-in-SAV for patients requiring reintervention for failed bioprosthese…
New data shows that TAV-in-TAV procedures result in lower pressure gradients than TAV-in-SAV, though mortality rates remain similar.
Pre-dilatation balloon aortic valvuloplasty may reduce post-dilatation needs in patients with aortic stenosis
Cardiology Meta-analysis
Pre-dilatation balloon aortic valvuloplasty may reduce post-dilatation needs in patients with aortic stenosis New data clarifies risks of balloon techniques for heart valves
Researchers evaluated the impact of pre-dilatation and post-dilatation techniques during transcatheter aortic valve implantation with self-e…
A large review shows that while some pre-procedure steps are safe, others may increase risks like mortality and leaks in certain heart valve…
SAPIEN 3 TAVR shows similar outcomes to SAVR regardless of annular size
Neurology RCT
SAPIEN 3 TAVR shows similar outcomes to SAVR regardless of annular size TAVR valve procedure shows similar results to surgery for aortic stenosis
This post hoc analysis of a randomized trial involving 925 low-risk patients with severe symptomatic aortic stenosis found that SAPIEN 3 TAV…
A new look at heart valve data shows that TAVR and surgical procedures offer similar safety and health outcomes regardless of patient anatom…
Staged PCI reduces severe kidney injury risk after TAVR in aortic stenosis and CAD
Cardiology Meta-analysis
Staged PCI reduces severe kidney injury risk after TAVR in aortic stenosis and CAD Staged heart procedures may lower risk of severe kidney injury
This meta-analysis of 7,119 patients with aortic stenosis and coronary artery disease undergoing TAVR found that staged PCI did not signific…
A new look at heart surgery data suggests that spacing out certain procedures could protect kidneys from severe damage.
General anesthesia increases in-hospital mortality risk (RR 1.99) and pneumonia incidence (RR 2.39) in TAVI procedures
Cardiology Meta-analysis
General anesthesia increases in-hospital mortality risk (RR 1.99) and pneumonia incidence (RR 2.39) in TAVI procedures General anesthesia may increase risks for patients with aortic stenosis
This meta-analysis of 23,848 patients evaluates the impact of general anesthesia versus non-general anesthesia during transcatheter aortic v…
Patients undergoing TAVI procedures may face higher risks of death and pneumonia when using general anesthesia instead of other sedation met…
Machine learning models outperform traditional scoring systems for predicting post-TAVR mortality risk
Cardiology Meta-analysis
Machine learning models outperform traditional scoring systems for predicting post-TAVR mortality risk Machine Learning Models Show Better Accuracy for TAVR Mortality Risk
This meta-analysis of 36 studies involving 272,390 patients evaluated various prediction models for mortality after TAVR. Machine learning m…
New analysis suggests machine learning tools may provide more accurate predictions of survival risk after heart valve replacement than stand…
AI research in aortic valve disease surges, focusing on diagnosis and risk stratification
Cardiology Sys. Review
AI research in aortic valve disease surges, focusing on diagnosis and risk stratification Artificial Intelligence Shows Growth in Aortic Valve Disease Research
This systematic review of 270 articles analyzes the growing role of artificial intelligence in aortic valve disease, particularly aortic ste…
New research highlights how artificial intelligence is becoming a major tool for diagnosing and predicting risks in aortic valve disease.
Early aortic valve intervention significantly reduces MACE compared to clinical surveillance in asymptomatic severe aortic stenosis
Cardiology Meta-analysis
Early aortic valve intervention significantly reduces MACE compared to clinical surveillance in asymptomatic severe aortic stenosis Early valve surgery reduces major heart events for aortic stenosis
This systematic review and meta-analysis of 3,086 patients found that early aortic valve intervention (AVR) results in a significant reducti…
New data shows that early surgical intervention can significantly reduce major heart complications for people with severe aortic stenosis.
Cusp-overlap technique reduces mortality and conduction disturbances in patients undergoing transcatheter aortic valve replacement
Cardiology Meta-analysis
Cusp-overlap technique reduces mortality and conduction disturbances in patients undergoing transcatheter aortic valve replacement New technique shows lower death rates for aortic valve surgery
This meta-analysis of clinical studies evaluates the cusp-overlap technique (COT) compared to a three-cusp coplanar approach in TAVR. The st…
A specific placement technique during heart valve replacement may reduce death rates and the need for permanent pacemakers in patients.
TAVR associated with higher 10-year mortality compared to surgery in intermediate-risk aortic stenosis
Radiology & Imaging RCT
TAVR associated with higher 10-year mortality compared to surgery in intermediate-risk aortic stenosis Trial shows surgery may offer better long term survival for aortic stenosis
This randomized trial of 1,910 patients with severe symptomatic aortic stenosis at intermediate surgical risk found that TAVR was associated…
A 10-year follow up of patients with aortic stenosis suggests that surgical treatment may have higher survival rates than TAVR procedures.