Review of two cases and three literature reports on prenatal double-chambered right ventricle outcomes

This publication is a review and case report focusing on the prenatal diagnosis of double-chambered right ventricle (DCRV). The scope includes a detailed discussion of two cases of type 1 DCRV and a review of three previously reported cases diagnosed prenatally. The setting involves antenatal diagnosis, with pregnancy outcomes serving as the primary outcome of interest.

The two cases discussed in detail demonstrated successful pregnancy outcomes. In contrast, the three previously reported cases associated with unfavorable pregnancy outcomes were included for comparison. Echocardiographic criteria such as tricuspid regurgitation, pulmonary blood flow velocity, and pressure differences were evaluated as secondary outcomes, though specific numerical results for these criteria were not reported in the provided data.

A key limitation acknowledged by the authors is that only three cases diagnosed prenatally have been reported in the literature to date. Consequently, the findings from two cases cannot be generalized to the broader population. Safety data, including adverse events and tolerability, were not reported for the cases discussed.

Practice relevance is not explicitly defined in the source text. Clinicians should interpret these findings cautiously given the small sample size and the disparity between the two successful cases and the three unfavorable historical cases.