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Quantitative PDA improves understanding and confidence versus qualitative PDA in dysplastic nevus screening

Quantitative PDA improves understanding and confidence versus qualitative PDA in dysplastic nevus…
Photo by Markus Winkler / Unsplash
Key Takeaway
Consider Quantitative PDA to improve understanding and confidence in dysplastic nevus screening.

This randomized A/B testing study evaluated the impact of Quantitative PDA versus Qualitative PDA on patient outcomes in 600 US adults with dysplastic nevus. The primary outcomes assessed included self-reported understanding, risk perception, confidence, and treatment intent. No follow-up duration was reported for this study.

Quantitative PDA improved self-reported understanding compared to Qualitative PDA, with a median score of 80 versus 72. This difference was statistically significant with a P value of .008. Quantitative PDA also improved confidence compared to Qualitative PDA, with a P value of .003. Additionally, Quantitative PDA lowered perceived melanoma risk for monitoring and for excision, with P values of .003 and less than .001 respectively.

Regarding treatment intent, Quantitative PDA did not change excision intent compared to Qualitative PDA. The absolute numbers for excision intent were 52% versus 53%, with an odds ratio of 1.04 and a 95% CI of 0.75-1.43. The P value for this comparison was .818. Dysplastic nevus severity significantly increased excision intent, with rates of 31% for mild, 41% for moderate, and 72% for severe lesions. This trend was significant with a P value of less than .001.

Safety data, including adverse events and discontinuations, were not reported. The study design was a randomized A/B testing study. The findings suggest that Quantitative PDA may enhance patient understanding and confidence without altering excision intent in this population.

Study Details

Study typeRct
EvidenceLevel 2
PublishedJun 2026
View Original Abstract ↓
BACKGROUND: Patient decision aids (PDAs) support shared decision-making by presenting treatment options clearly and objectively. However, little is known about how risk framing and diagnostic severity labels influence patient preferences in dermatology. OBJECTIVE: Assess how PDA format (quantitative vs qualitative) and dysplastic nevus severity (mild, moderate, or severe) affect understanding, risk perception, confidence, and treatment intent. METHODS: In this randomized A/B testing design, 600 US adults viewed a quantitative or qualitative PDA describing a mild, moderate, or severe dysplastic nevus scenario. Self-reported outcomes included understanding, treatment selection (excision vs monitoring), satisfaction, decision-making confidence, perceived melanoma risk, and concern. Analyses used nonparametric tests and logistic regression. RESULTS: Quantitative PDAs improved self-reported understanding (median 80 vs 72; P = .008) and confidence (P = .003) and lowered perceived melanoma risk for monitoring (P = .003) and excision (P < .001), but did not change excision intent (52% vs 53%; odds ratio 1.04, 95% CI 0.75-1.43; P = .818). Dysplastic nevus severity significantly increased excision intent (31% mild, 41% moderate, 72% severe; P < .001), without affecting understanding. CONCLUSION: Quantitative PDAs enhance comprehension, yet diagnostic severity labels predominantly drive treatment intent. Approximately one-third of participants diverged from expert recommendations despite high comprehension, underscoring that individual values drive treatment choices.
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