Quantitative PDA improves understanding and confidence versus qualitative PDA in dysplastic nevus screening
This randomized A/B testing study evaluated the impact of Quantitative PDA versus Qualitative PDA on patient outcomes in 600 US adults with dysplastic nevus. The primary outcomes assessed included self-reported understanding, risk perception, confidence, and treatment intent. No follow-up duration was reported for this study.
Quantitative PDA improved self-reported understanding compared to Qualitative PDA, with a median score of 80 versus 72. This difference was statistically significant with a P value of .008. Quantitative PDA also improved confidence compared to Qualitative PDA, with a P value of .003. Additionally, Quantitative PDA lowered perceived melanoma risk for monitoring and for excision, with P values of .003 and less than .001 respectively.
Regarding treatment intent, Quantitative PDA did not change excision intent compared to Qualitative PDA. The absolute numbers for excision intent were 52% versus 53%, with an odds ratio of 1.04 and a 95% CI of 0.75-1.43. The P value for this comparison was .818. Dysplastic nevus severity significantly increased excision intent, with rates of 31% for mild, 41% for moderate, and 72% for severe lesions. This trend was significant with a P value of less than .001.
Safety data, including adverse events and discontinuations, were not reported. The study design was a randomized A/B testing study. The findings suggest that Quantitative PDA may enhance patient understanding and confidence without altering excision intent in this population.