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Narrative review suggests endovascular treatment may be feasible and safe for posterior epistaxis

Narrative review suggests endovascular treatment may be feasible and safe for posterior epistaxis
Photo by Dmytro Vynohradov / Unsplash
Key Takeaway
Consider endovascular treatment for posterior epistaxis cautiously, noting risk of stroke from dangerous anastomoses.

A narrative review based on a semi-systematic search examined the role of endovascular treatment in patients with posterior epistaxis. The review compared endovascular approaches to traditional management methods, though specific comparator details and primary outcomes were not reported. The main finding was that endovascular treatment appears to be a feasible and safe option, but the review did not provide specific effect sizes, absolute numbers, or statistical measures to quantify this assessment.

Regarding safety, the review noted the potential for serious complications, including stroke or blindness, from inadvertent embolization in dangerous communications around the skull base. Specific rates of adverse events, serious adverse events, or treatment discontinuations were not reported. The authors emphasized that thorough angiographic assessment is required before proceeding with endovascular treatment to identify these hazardous anastomoses.

Key limitations include the narrative and semi-systematic nature of the review; the certainty of the evidence is therefore limited. Sample size, follow-up duration, and specific study settings for the included evidence were not reported. The review's conclusions are based on association, not causation, and do not establish efficacy or superiority over traditional approaches.

For practice, the authors suggest endovascular treatment could be a viable option for posterior epistaxis and should not be reserved solely as a last resort. However, this recommendation is tempered by the evidence's narrative quality and the serious, albeit rare, risk of catastrophic neurological complications. Clinicians must weigh these potential benefits against the procedural risks and the limited comparative effectiveness data available.

Study Details

Study typeSystematic review
EvidenceLevel 1
PublishedApr 2026
View Original Abstract ↓
Posterior epistaxis is a common otorhinolaryngological emergency that often presents a clinical challenge and typically needs aggressive management. Endovascular therapy has emerged as a strong alternative to traditional approaches. However, it is still considered a last-resort option for intractable cases in most clinical guidelines and among many physicians managing this condition. The purpose of this narrative review is to provide a comprehensive overview of posterior epistaxis, with a particular focus on its vascular anatomy and the role of endovascular treatment. Articles were retrieved from MEDLINE, Scopus and Web of Science using a semi-systematic search strategy. Posterior epistaxis is a challenging condition due to its variable etiologies and numerous risk factors. Effective treatment requires careful consideration of the region's complex and variable vascular anatomy, including potentially dangerous anastomoses. The results indicate that endovascular treatment is a feasible and safe option; however, it should always be preceded by a thorough angiographic assessment to identify the exact vascular anatomy and site of bleeding. This also helps to identify potentially dangerous communications around the skull base, where inadvertent embolization can lead to complications such as stroke or blindness. Posterior epistaxis is a complex condition that requires a comprehensive approach. Performing an angiography before treatment can help pinpoint the bleeding site, as well as identify any dangerous communications. Endovascular treatment could be a viable and safe option in cases of posterior epistaxis and should not be reserved solely as a last resort.
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