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CDC recommends approaches to maintain tuberculin skin testing during expected Aplisol shortageCDC issues guidance during expected shortage of tuberculosis skin test antigen

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Key Takeaway
Note CDC guidance for maintaining TB skin testing during expected Aplisol shortage.

The Centers for Disease Control and Prevention (CDC) has published recommendations addressing an expected shortage of Aplisol, a tuberculin skin test antigen. The publication type is listed as 'OTHER,' and key methodological details including study type, population, sample size, setting, and follow-up duration are not reported. No specific intervention or comparator was described in the available evidence.

The main finding is that the CDC recommends general approaches to prevent a reduction in tuberculin skin testing capability. No quantitative results, effect sizes, or outcome data are provided. Safety and tolerability information, including adverse events and discontinuations, are also not reported.

Key limitations include the absence of a formal study design and the lack of reported data on the effectiveness of the recommended approaches. The practice relevance is limited to awareness of official CDC guidance for contingency planning. Clinicians should consult the full CDC recommendations for specific operational details.

The Centers for Disease Control and Prevention (CDC) has issued guidance for healthcare providers. This is because of an expected shortage of a product called Aplisol. Aplisol is one of the antigens used to perform tuberculin skin tests, which check for tuberculosis (TB) infection.

The CDC's guidance offers general approaches to help clinics and hospitals continue offering TB skin tests during the shortage. The announcement does not describe a specific study with patients or report new research results. Instead, it is a public health notice about a supply chain problem.

There are no new safety concerns or medical findings reported with this announcement. The main reason for caution is that this is administrative guidance, not evidence from a clinical trial. Readers should know that health officials are planning for a potential shortage to keep TB testing available.

What this means for you:
CDC provides planning guidance for clinics due to an expected shortage of a TB test product.

Study Details

EvidenceLevel 5
PublishedJun 2019
View Original Abstract ↓
CDC recommends general approaches to prevent a reduction in tuberculin skin testing capability resulting from the expected shortage of Aplisol.
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