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Exercise Improves Body Composition and Function in Sarcopenic ObesityExercise helps older adults with sarcopenic obesity build muscle and lose fat

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Key Takeaway
Exercise significantly improves body composition and physical function in sarcopenic obesity, but metabolic benefits are less certain.

This systematic review and meta-analysis evaluates the effects of exercise interventions on body composition, metabolic health, and physical function in older adults with sarcopenic obesity. The analysis included 917 participants across multiple studies, examining outcomes such as body mass index (BMI), body fat mass (BFM), body fat percentage (PBF), low-density lipoprotein cholesterol (LDL-C), appendicular skeletal muscle (ASM), skeletal muscle index (SMI), handgrip strength (HG), gait speed (GS), knee extension strength (KES), and insulin-like growth factor 1 (IGF-1).

Exercise interventions led to statistically significant reductions in BMI (MD = -0.51, 95%CI: -0.76 to -0.25), BFM (MD = -1.74, 95%CI: -2.67 to -0.81), PBF (MD = -2.64, 95%CI: -3.27 to -2.00), and LDL-C (MD = -7.17, 95%CI: -13.62 to -0.71). These findings indicate clinically meaningful improvements in adiposity and lipid profile.

Concurrently, exercise significantly increased ASM (MD = 0.34, 95%CI: 0.13 to 0.55), SMI (MD = 0.21, 95%CI: 0.10 to 0.32), HG (SMD = 0.97, 95%CI: 0.47 to 1.47), GS (MD = 0.14, 95%CI: 0.07 to 0.21), KES (SMD = 0.36, 95%CI: 0.06 to 0.65), and IGF-1 (SMD = 0.65, 95%CI: 0.30 to 1.00). These results demonstrate enhanced muscle mass, strength, and functional capacity.

The evidence for body composition and physical function outcomes was graded as moderate certainty, while metabolic health outcomes (LDL-C, IGF-1) were low certainty. The authors caution that the beneficial effects are not supported by high-quality evidence due to methodological limitations across included studies.

Limitations include heterogeneity in exercise protocols, small sample sizes in some trials, and lack of standardized diagnostic criteria for sarcopenic obesity. No adverse events or discontinuations were reported, but safety data were limited.

For clinicians, these findings support prescribing structured exercise—combining resistance and aerobic training—to improve body composition and physical function in older adults with sarcopenic obesity. However, the low certainty for metabolic benefits suggests that exercise alone may not suffice for lipid management, and adjunctive therapies should be considered.

Future research should focus on high-quality randomized controlled trials with standardized outcomes, longer follow-up, and assessment of patient-important endpoints such as falls, fractures, and quality of life.

Many older adults face a difficult health challenge known as sarcopenic obesity. This condition combines two problems: losing muscle mass while carrying too much body fat. This mix makes it harder to move, weakens the heart, and increases the risk of falling. For years, doctors have wondered if exercise could fix this specific problem. A new systematic review and meta-analysis looked at the answer. This research combined data from many studies to see if movement really helps these patients.

The researchers analyzed information from 917 older adults who participated in various exercise programs. These people had the specific mix of low muscle and high fat. The goal was to see if physical activity could change their bodies in a good way. The study looked at many different measures to see how the participants changed over time.

The results were encouraging for those who want to stay active. The exercise programs led to a significant drop in body mass index, which is a common way to track weight. Participants also lost body fat mass and their body fat percentage went down. This means the exercise helped them get leaner without just losing water weight.

More importantly, the exercise helped build muscle. The amount of muscle in the arms and legs increased. This is crucial because strong muscles help older adults walk faster and stand up from chairs easily. Their grip strength improved, meaning they could hold things tighter. Their ability to extend their knees also got stronger. These physical changes mean they can move around their homes with more confidence and less fear of falling.

The study also found improvements in cholesterol levels and a hormone called insulin-like growth factor 1. However, the researchers were careful about what they said. They noted that the evidence for these health benefits was not based on the highest quality studies. There were some methodological issues that need to be fixed to make the results even more certain. Because of this, the certainty of the evidence is moderate for body changes but low for metabolic health.

Safety was a major part of the review. No serious side effects or problems were reported. People did not stop their exercise programs due to trouble tolerating the activity. This suggests that moving more is safe for this group. However, people should not overreact to this single study. The evidence is not perfect, and more high-quality research is needed. For now, the message is clear: older adults with sarcopenic obesity can likely benefit from exercise to build muscle and lose fat.

What this means for you:
Moderate evidence suggests exercise helps older adults with sarcopenic obesity build muscle and lose fat safely.

Study Details

Study typeMeta analysis
Sample sizen = 917
EvidenceLevel 1
PublishedJun 2026
View Original Abstract ↓
Exercise interventions benefit body composition, physical function, and metabolic health in older adults with sarcopenic obesity (SO), but the comparative effects of different types of exercise remain unclear. This study conducted a systematic review and meta-analysis of randomized controlled trials (RCTs) to evaluate overall and type-specific effects. Six databases were systematically searched up to December 2025. Twenty RCTs with a total of 917 participants (mean age 64.1-81.4 years) were included. Overall, exercise significantly reduced body mass index (BMI; MD = -0.51; 95%CI: -0.76 to -0.25), body fat mass (BFM; MD = -1.74; 95%CI: -2.67 to -0.81), body fat percentage (PBF; MD = -2.64; 95%CI: -3.27 to -2.00), and low-density lipoprotein cholesterol (LDL-C; MD = -7.17; 95%CI: -13.62 to -0.71), and increased appendicular skeletal muscle (ASM; MD = 0.34; 95%CI: 0.13 to 0.55), skeletal muscle index (SMI; MD = 0.21; 95%CI: 0.10 to 0.32), handgrip strength (HG; SMD = 0.97; 95%CI: 0.47 to 1.47), gait speed (GS; MD = 0.14; 95%CI: 0.07 to 0.21), knee extension strength (KES; SMD = 0.36; 95%CI: 0.06 to 0.65), and insulin-like growth factor 1 (IGF-1; SMD = 0.65; 95%CI: 0.30 to 1.00). Subgroup analyses demonstrated that resistance training (RT) significantly reduced PBF, and significantly increased ASM, SMI, HG, KES, and IGF-1. Combined training (CT) significantly reduced BMI and PBF, and improved SMI, HG, GS, and IGF-1. Our systematic review and meta-analysis of studies of older adults with SO indicates that the beneficial effect of exercise is not supported by high-quality evidence. Moderate-certainty evidence does suggest statistically significant benefits for body composition and physical function, while low-certainty evidence suggests trivial effects for metabolic health. Future high-quality RCTs addressing methodological issues are needed to improve the certainty of the evidence and to further investigate the optimal type of exercise for this population.
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