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Asparagus officinalis L. polysaccharides show proven anti-inflammatory and anti-non-alcoholic liver disease effects in a review

Asparagus officinalis L. polysaccharides show proven anti-inflammatory and anti-non-alcoholic…
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Key Takeaway
Note that Asparagus officinalis L. polysaccharides show proven anti-inflammatory and anti-non-alcoholic liver disease effects.

This review examines the potential health benefits of Asparagus officinalis L. polysaccharides (AOPs). The scope includes conditions such as non-alcoholic liver disease, atherosclerosis, and neuritis. The authors do not report a specific study population or sample size. Instead, they synthesize evidence regarding secondary outcomes like cytotoxic effects, pro-apoptotic effects, immune regulation, regulation of intestinal flora, and anti-inflammatory effects.

The review concludes that cytotoxic effects, pro-apoptotic effects, immune regulation, and anti-neuritis are proven. Additionally, anti-atherosclerosis and anti-non-alcoholic liver disease effects are proven. The regulation of intestinal flora is described as the most important health benefit. No specific effect sizes, absolute numbers, or p-values are provided in the source text.

Safety and tolerability were not reported. Adverse events, serious adverse events, discontinuations, and tolerability data are absent from the input. The review does not overstate certainty regarding these findings. Funding or conflicts of interest were not reported. The authors note that this work provides a valuable reference for the reuse of other natural plant waste.

Study Details

Study typeSystematic review
EvidenceLevel 1
PublishedJun 2026
View Original Abstract ↓
Asparagus officinalis L. (A. officinalis) is a highly representative plant in the Asparagus L. genus, with both edible and medicinal values. As a typical macromolecular metabolite in A. officinalis, A. officinalis L. polysaccharides (AOPs) have attracted much attention due to its rich functional biopolymer properties. AOPs have been proven to have cytotoxic and pro-apoptotic effects, immune regulation, and regulation of intestinal flora, anti-neuritis, anti-atherosclerosis, anti-non-alcoholic liver disease, and other health benefits. Among them, regulation of intestinal flora is the most important health benefit of AOPs. In addition, researchers have developed corresponding drug formulations based on their anti-inflammatory, cytotoxic, and pro-apoptotic effects in practical applications. Through a review of previous studies, researchers have found that plant residues extracted from A. officinalis can be developed into high-value cellulose nanocrystals. This also provides a valuable reference for the reuse of other natural plant waste. In this study, we summarize and review research on AOPs’ phytochemical structures, biomedical, and industrial applications, based on the latest research findings and practical considerations.
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