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Scoping review maps burden of diabetic emergencies in African healthcare settingsDiabetic emergencies in Africa show wide variation in rates and outcomes

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Key Takeaway
Note high mortality and variable prevalence of diabetic emergencies in African settings.

This scoping review examines patterns and the burden of diabetic emergencies among people with diabetes in Africa. The authors analyzed 25 studies to understand the landscape of these conditions in the region. The scope includes diabetic ketoacidosis, hyperosmolar hyperglycemic state, and hypoglycemia as primary conditions of interest.

The review found that 17 studies reported diabetic ketoacidosis with proportions ranging from 2.0% to 92.6%. Eleven studies reported hyperosmolar hyperglycemic state with proportions from 4.5% to 50.6%. Nine studies reported hypoglycemia with proportions from 0.8% to 28.3%. These wide ranges suggest significant heterogeneity in reporting or prevalence across different settings.

Adverse outcomes were substantial. In-hospital mortality ranged from 5% to 17.1%. DKA case fatality reached 30% in some studies. Median hospital stay ranged from 6 to 9 days. The authors note that these conditions place a heavy strain on African healthcare systems and are a major cause of illness and death.

The review does not establish causality or provide definitive treatment recommendations. The findings reflect the current state of knowledge and the challenges in managing these emergencies. Clinicians should recognize the high burden and variability in outcomes for people with diabetes in Africa.

A new scoping review looked at 25 studies about diabetic emergencies in Africa. These emergencies include diabetic ketoacidosis (DKA), hyperosmolar hyperglycemic state (HHS), and hypoglycemia. The goal was to understand how often these events happen and how severe they are for people with diabetes in Africa.

The review found big differences in how often these emergencies were reported. For DKA, the rate in studies ranged from 2% to 93%. For HHS, it was 4% to 51%. Hypoglycemia was reported in 0.8% to 28% of cases. This shows that the burden of these emergencies is not the same across the continent.

When it comes to outcomes, the results are also concerning. In-hospital death rates ranged from 5% to 17%. For DKA specifically, the case fatality rate could reach 30% in some places. The median hospital stay was 6 to 9 days, which is a long time for patients and their families.

These findings highlight that diabetic emergencies are a major cause of illness and death in Africa. They put a heavy strain on healthcare systems. More work is needed to prevent these events and improve care for people with diabetes in the region.

What this means for you:
Diabetic emergencies in Africa have high death rates and long hospital stays, showing a major need for better prevention and care.

Study Details

Study typeSystematic review
EvidenceLevel 1
PublishedMay 2026
View Original Abstract ↓
This scoping review aimed to map the evidence on the patterns and burden of diabetic emergencies among people with diabetes in Africa. The review followed the Levac et al. framework and the PRISMA-ScR guidelines. A systematic search was conducted across five electronic databases (CINAHL, Embase, MEDLINE, Scopus, and Web of Science), and manual searches in Google and Google Scholar were conducted for studies published between 2015 and 2025. From 1,207 records, 25 studies met the inclusion criteria. Extracted data were analyzed using thematic analysis and descriptive numerical summaries. Of the 25 reviewed studies, diabetic ketoacidosis (DKA) was the most commonly reported emergency, appearing in 17 studies, with proportions ranging from 2.0% to 92.6%. This was followed by hyperosmolar hyperglycemic state (HHS), reported in 11 studies (4.5%–50.6%), and hypoglycemia, reported in 9 studies (0.8%–28.3%). Common determinants included infections and intercurrent illness, poor glycemic control, treatment non-adherence or discontinuation, and limited access to ongoing care. Reported in-hospital mortality ranged from 5% to 17.1%, with DKA case fatality reaching 30% in some studies. Median hospital stay generally ranged from 6 to 9 days. Diabetic emergencies are a major, yet largely preventable, cause of illness and death among people with diabetes in Africa. Conditions such as DKA place a heavy strain on African healthcare systems. To reduce the rates of these avoidable complications, it is essential to improve primary care for early detection and ensure consistent access to insulin and glucose monitoring.
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