Survey of U.S. adults links religious and political factors to mRNA vaccine attitudes
An observational survey study analyzed attitudes toward mRNA vaccines among 4939 U.S. adults from six religious groups (Black Protestant, Catholic, Evangelical Protestant, Jewish, Mainline Protestant, Muslim) and atheist, agnostic, or spiritual individuals. The study examined how religious affiliations, beliefs, practices, political orientation, and distrust in healthcare related to self-reported support for and concerns about mRNA vaccines, without a primary clinical outcome.
Regarding support, Evangelical Protestant participants showed significantly less support than other groups, while atheist participants were the most supportive. For concerns, Muslim participants had the highest concerns, and atheist participants had the lowest. The strongest predictors of greater support were more spiritual community support for community health, higher acceptance of evolution, more liberal political orientation, and less distrust toward the healthcare system. The strongest predictors of greater concerns were more distrust toward the healthcare system and more conservative political orientation.
No safety or tolerability data related to vaccine administration were reported, as this was a survey of attitudes. Key limitations include the observational, cross-sectional design, which precludes causal inference, and reliance on self-reported attitudes rather than clinical behaviors or outcomes. The findings describe associations between sociocultural factors and vaccine attitudes in a specific U.S. population at a point in time. The practice relevance is not explicitly reported, but the data may inform understanding of population-level sentiment drivers.
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