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Functional appliances induce significant three-dimensional condylar changes and forward positioning in Class II malocclusionFunctional Appliances Cause Changes in Jaw Joint Structure

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Key Takeaway
Note that functional appliances induce significant condylar growth, but evidence for glenoid fossa remodeling is inconsistent.

This systematic review evaluates the effects of functional appliance therapy, specifically Twin block and Herbst appliances, on three-dimensional changes in condylar morphology, position, and glenoid fossa remodeling in growing patients with Class II malocclusion. The analysis synthesized data from 258 patients to assess how these appliances influence the temporomandibular joint (TMJ).

Findings indicate that Twin Block appliances result in significant increases in condylar volume and forward positioning. In contrast, Herbst appliances lead to modest increases in condylar dimensions while maintaining relatively stable condyle-fossa relationships. Overall TMJ changes were characterized as mild to moderate with notable variability across the included studies. However, evidence regarding glenoid fossa remodeling was reported inconsistently and is considered limited.

The authors note that the evidence is heterogeneous and inconclusive, particularly concerning the specific extent of glenoid fossa remodeling. While functional appliances are shown to induce adaptive three-dimensional changes in the condyle, the degree to which these TMJ adaptations contribute to overall treatment outcomes remains modest. Clinical application should account for this variability and the inconsistent reporting of certain anatomical remodelings.

How this fits prior evidence

This systematic review extends the existing evidence regarding functional appliances for Class II malocclusion by specifically detailing three-dimensional condylar changes. It complements the finding that Herbst offers modest advantages in mentolabial angle and molar relationship over Twin Block, while providing specific data on how each appliance type influences condylar volume and position.

Researchers looked at how two types of dental devices, called functional appliances, affect the growth of the jaw joints in children with a specific bite alignment known as Class II malocclusion. They reviewed data from 258 patients to see how these devices changed the shape and position of the bone structures over time.

The study found that Twin Block appliances led to significant increases in condylar volume and moved the jaw forward. In contrast, Herbst appliances showed more modest changes to the size of the joint while keeping the relationship between the joint and its socket relatively stable. These findings suggest that different devices can affect the jaw's growth in different ways.

It is important to note that the evidence for some changes, like how the bone socket reshapes itself, was inconsistent across studies. Because the data is varied and not always clear, these results are currently considered inconclusive for certain parts of the joint. These findings show that while jaw joints do adapt during treatment, the extent of those changes varies depending on the specific device used.

What this means for you:
Different dental appliances can cause different amounts of growth and movement in the jaw joint during treatment.

Common questions

What happens to the jaw joint during treatment?

The study found that functional appliances cause mild to moderate changes in the jaw joints. Specifically, Twin Block appliances were linked to significant increases in condylar volume and forward positioning of the mandible. These results suggest that the jaw joint adapts as part of the orthodontic process.

Are there differences between Twin Block and Herbst appliances?

Yes, the two devices showed different effects. Twin Block appliances led to significant increases in condylar volume and position. Herbst appliances resulted in more modest increases in condylar dimensions while keeping the relationship between the condyle and the fossa relatively stable.

Is it certain how much the jaw joint changes?

The evidence is currently considered heterogeneous and inconclusive for some specific areas. For example, reports on glenoid fossa remodeling were inconsistent across the studies reviewed. Because of this variability, the exact extent of these changes is not fully clear.

Study Details

Study typeMeta analysis
EvidenceLevel 1
PublishedJun 2026
View Original Abstract ↓
Functional appliance therapy is widely used for the management of Class II malocclusion in growing patients, aiming to enhance mandibular growth through anterior repositioning of the mandible. This forward positioning is believed to induce adaptive remodeling within the temporomandibular joint (TMJ), particularly in the condyle and glenoid fossa. With the advent of cone-beam computed tomography (CBCT), three-dimensional evaluation of these structures has become more precise, however, existing evidence remains heterogeneous and inconclusive. To systematically evaluate three-dimensional changes in condylar morphology, position, and glenoid fossa remodeling following functional appliance therapy in growing patients with Class II malocclusion. This systematic review was conducted in accordance with PRISMA guidelines and registered in PROSPERO (CRD420261379151). Electronic databases including PubMed, Scopus, Web of Science, Cochrane Library, and Google Scholar were searched up to December 2025. Studies involving growing patients treated with functional appliances and assessed using CBCT were included. Data extraction and quality assessment were performed independently by two reviewers using the Newcastle–Ottawa Scale and RoB 2 tool. Due to heterogeneity, a narrative synthesis was undertaken. Seven studies comprising 258 patients were included. Twin Block appliances demonstrated significant increases in condylar volume and forward positioning, whereas Herbst appliances showed modest increases in condylar dimensions with relatively stable condyle–fossa relationships. Glenoid fossa remodeling was inconsistently reported. Overall, TMJ changes were mild to moderate, with variability across studies. Functional appliances induce adaptive three-dimensional changes in the condyle, while glenoid fossa remodeling is limited and inconsistent. Skeletal correction in Class II malocclusion appears multifactorial, with TMJ adaptation contributing modestly to treatment outcomes.
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