A large review of 368 studies analyzed E. coli bacteria found in humans, animals, food, and the environment in Iran. The study looked at how well these bacteria resist common antibiotics and the specific genes that allow them to survive treatment.
The findings show a high level of resistance to Penicillins, which was reported at 71.7 percent. In contrast, resistance to Fosfomycin was much lower at 6.8 percent. The review also noted that resistance to several other antibiotics, including Ceftizoxime, Ertapenem, Streptomycin, Piperacillin-Tazobactam, and Colistin, has increased over time.
These results highlight a growing concern regarding how effectively current medicines can treat infections. Because the data comes from a broad review of existing studies rather than a single clinical trial, it serves as a baseline for policy making. It emphasizes the need for better management of antibiotics to ensure they remain effective for patients in the future.