Oral fosfomycin noninferior to intravenous carbapenems for clinical cure in ESBL-producing Enterobacterales UTIs
Oral fosfomycin shows promise for treating complicated urinary tract infections
This multicenter, open-label, randomized noninferiority trial evaluated 299 adults with complicated UTIs caused by ESBL-producing Enterobact…
Patients with complicated urinary tract infections may be able to switch from IV drugs to oral fosfomycin with similar success rates.
E. coli isolates in Iran show 71.7% resistance to penicillins and 47.2% ESBL production
Rising Antibiotic Resistance in E. coli Bacteria Found in Iran
This meta-analysis of 368 studies evaluates antimicrobial resistance in E. coli across human, animal, and environmental samples in Iran. The…
New data shows high levels of antibiotic resistance in E. coli bacteria across humans, animals, and the environment in Iran.
Pharmacokinetic and clinical data inform therapeutic selection for difficult to treat Pseudomonas aeruginosa CNS infections
New strategies help treat drug resistant brain infections
This narrative review evaluates the feasibility of various antimicrobial agents, including ceftolozane-tazobactam, ceftazidime-avibactam, az…
Doctors are finding new ways to treat serious brain infections caused by bacteria that have become hard to kill with standard medicine.
Intravesical aminoglycoside instillations reduce recurrent urinary tract infection risk with an IRR of 0.23
New findings show ways to reduce recurring urinary tract infections
This systematic review and meta-analysis of 25 studies evaluates intravesical instillations for preventing recurrent urinary tract infection…
Doctors are looking at new ways to stop repeat urinary tract infections using local treatments like aminoglycosides or hyaluronic acid.
Microplastic biofilms enrich antibiotic resistance genes in freshwater environments
Microplastics in water carry dangerous antibiotic resistance genes
This meta-analysis of environmental studies found that microplastic biofilms in freshwater settings significantly enrich antibiotic resistan…
Tiny plastic particles in freshwater environments gather antibiotic resistance genes more than the water itself. This review found that non-…
Nitrofurantoin outperforms single-dose fosfomycin for uncomplicated UTIs in Spanish primary care
Nitrofurantoin beats single-dose fosfomycin for common bladder infections in women
This Phase 4 randomized clinical trial evaluated four antibiotic regimens in women with uncomplicated urinary tract infections in Spanish pr…
New research shows nitrofurantoin works better than single-dose fosfomycin for curing common bladder infections in women.