Trypanosomatidae Infection Prevalence in South American Coatis From Brazilian Urban Forest Fragments (110)
This investigation utilized a cohort study design to assess Trypanosomatidae species infection in South American coatis (Nasua nasua). The study included a sample size of 110 animals located in urban forest fragments in the Brazilian Midwest, specifically Campo Grande, CG. No comparator group was utilized in this observational analysis. The setting was restricted to these specific geographic locations within the study parameters.
The primary outcome focused on the diversity of trypanosomatid species. The nPCR positivity rate was 36.4%, corresponding to 40 of 110 subjects. The combined SSU rRNA detection and sequencing positivity rate was 47.3%, representing 52 of 110 subjects. Single Trypanosomatidae infections occurred in 36.4% of the cohort (40/110), while mixed Trypanosomatidae infections were observed in 10.9% (12/110). These results highlight the infection burden within this specific wildlife population.
Safety data regarding adverse events, serious adverse events, discontinuations, and tolerability were not reported in the provided evidence. Limitations and practice relevance were also not reported. As this study involved non-human subjects, direct clinical application to human patients is not supported by the current data. Clinicians should recognize the specific wildlife context when interpreting these prevalence figures. No conclusions regarding causality or certainty were provided in the source material. Further investigation is needed to establish broader applicability.
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