Fatal Naegleria fowleri infection reported in patient exposed to Arkansas splash pad water

A case report describes a fatal case of Naegleria fowleri meningoencephalitis in one patient. The exposure was linked to water from a splash pad in Pulaski County, Arkansas. The primary outcome was fatal infection, with 1 fatal case reported. No comparator group, follow-up duration, or specific effect size data were provided.

Safety and tolerability data were not reported. The report did not detail adverse events, serious adverse events, or treatment discontinuations. The funding sources and potential conflicts of interest were also not reported.

Key limitations include the nature of the evidence as a single case report. The report describes an association but cannot establish causality or quantify risk. No specific practice recommendations were provided, and the relevance to broader clinical practice is limited by the lack of comparative data and population-level risk assessment.