Possible mpox exposures described in patients without reported male-to-male sexual contact

An observational report from six U.S. jurisdictions described possible mpox exposures among patients diagnosed with mpox who did not report male-to-male sexual contact. The study aimed to characterize transmission routes beyond this primary risk group. No comparator group, sample size, or specific follow-up period was reported.

The main outcome was a description of possible exposures, but the report did not provide the specific exposures identified, effect sizes, absolute numbers, or statistical measures. The direction of findings and any quantitative results were not reported. No safety or tolerability data were presented.

Key limitations include the observational design, which cannot establish causality, and the absence of reported sample size, specific exposures, and quantitative results. The funding sources and conflicts of interest were not reported. The practice relevance is unclear due to the incomplete reporting of findings. This report highlights a data gap regarding mpox transmission in populations outside the primary risk group but provides no actionable clinical conclusions.