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Serenity therapy reduces symptoms and improves coping in geriatric hemodialysis patientsCan a calming therapy ease the heavy burden of dialysis for older patients?

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Key Takeaway
Consider serenity therapy as preliminary psychosocial support for geriatric hemodialysis patients; evidence is single-center with unreported effect sizes.

A single-center randomized controlled trial in Egypt evaluated serenity therapy in 80 geriatric patients with end-stage renal disease undergoing hemodialysis. The intervention was administered over five months, though the specific comparator was not reported. The study assessed psychosocial outcomes including hemodialysis symptoms (occurrence, frequency, severity, distress), coping styles, and emotional regulation.

Results showed statistically significant reductions in hemodialysis symptoms (P < 0.05) and improvements in both coping strategies and emotional regulation (both P < 0.05). However, the study did not report effect sizes, confidence intervals, or absolute numerical changes for these outcomes. The RCT design suggests causal inference is possible for these measured psychosocial outcomes within the study context.

Safety and tolerability data were not reported, including adverse events, serious adverse events, or discontinuation rates. Key limitations include the single-center setting in Egypt, unspecified comparator, and lack of reported effect magnitude. The study did not assess clinical endpoints like survival or hospitalization.

Practice relevance is restrained to suggesting serenity therapy may be a component of psychosocial support for geriatric hemodialysis patients, but evidence is preliminary. Clinicians should note the lack of comparison to other supportive therapies and the absence of safety data before considering implementation.

Imagine spending hours each week hooked to a dialysis machine, dealing with fatigue, cramps, and the emotional weight of a chronic illness. For older adults, this reality can be overwhelming. A new study tested whether 'serenity therapy'—a psychological approach aimed at fostering peace and acceptance—could lighten that load.

The research followed 80 older patients at a single dialysis center in Egypt for five months. Those who received the therapy reported significant reductions in how often, how severely, and how much their dialysis symptoms bothered them. They also showed improvements in how they coped with their illness and managed their emotions. The study's design makes it likely the therapy caused these positive changes.

However, this is an early, hopeful signal, not a definitive answer. We don't know the size of the benefit—was it a major shift or a modest one? The study didn't compare serenity therapy to another treatment or a placebo, so we can't say if it's better than other support options. It also didn't report on safety or if anyone dropped out. The results are from one specific group of patients, so we can't yet assume it would work the same for everyone on dialysis.

What this means for you:
A therapy focused on inner peace helped older dialysis patients feel better and cope, but more research is needed.

Study Details

Study typeRct
Sample sizen = 80
EvidenceLevel 2
PublishedApr 2026
View Original Abstract ↓
BACKGROUND: Serenity therapy shows promise as a complementary intervention addressing psychosocial and physical aspects for geriatric patients with End-Stage Renal Disease (ESRD). However, its efficacy in those undergoing hemodialysis remains underexplored. AIM: This study aims to investigate the effects of serenity therapy on symptoms of distress, coping styles, and emotional regulation among geriatric hemodialysis patients. METHODS: A randomized controlled trial was conducted with 80 patients from a hemodialysis unit in El-Behaira Governorate, Egypt, over five months. Data were collected using a four-section questionnaire, including socio-demographic information, a Hemodialysis Symptoms Distress scale, a Brief-COPE, and an Emotion Regulation Questionnaire. RESULTS: Post-intervention evaluations revealed significant reductions in the occurrence, frequency, severity, and distress of hemodialysis symptoms, alongside improvements in coping strategies and emotional regulation (P < 0.05). CONCLUSION: Serenity therapy effectively alleviates hemodialysis symptoms and enhances coping and emotional regulation in geriatric patients. TRIAL REGISTRATION: Registered with ClinicalTrials.gov on 4/02/2024; registration number "NCT06255184".
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