Hybrid EDF intraocular lens matches monofocal for distance, improves intermediate and near vision

This prospective, comparative, single-center study evaluated a novel bifocal hybrid extended depth-of-focus (EDF) intraocular lens, AM2UH, against a monofocal IOL, AW-UV. Thirty-seven patients (37 eyes) were implanted with AM2UH and 36 patients (36 eyes) were implanted with AW-UV. Assessments occurred at 6 months postoperatively.

Evaluated outcomes included uncorrected and distance-corrected visual acuity, defocus curves, refractive outcomes, contrast sensitivity, and visual quality questionnaires, with comparisons between the two groups. The abstract does not designate primary versus secondary outcomes and does not describe randomization; the design is comparative rather than explicitly randomized.

For the main results, AM2UH was non-inferior to AW-UV for monocular corrected distance visual acuity (p > 0.05) and superior for intermediate and near visual acuity. The abstract's reported p-value text for the intermediate and near comparisons is truncated, so exact thresholds beyond the distance comparison are not fully available. The authors conclude that AM2UH provides satisfactory distance and intermediate vision, improved near vision, an extended visual range, and favorable visual quality.

Safety data, adverse events, contrast sensitivity values, defocus curve figures, and questionnaire scores are not quantified in the abstract text provided. No funding, conflicts of interest, country, or center identity are reported in the abstract.

Limitations evident from the abstract include a single-center comparative design, a small sample (37 vs 36 eyes), short 6-month follow-up, and absence of numerical effect sizes or safety detail in the available text. Clinicians considering EDF options for cataract surgery may view these findings as preliminary evidence that the AM2UH lens can extend intermediate and near function while preserving distance acuity, pending larger, longer, multi-center data.