10 Hz rTMS over SMA enhances balance in stroke patients with balance disorders.

This randomized controlled trial investigated the effects of 10 Hz repetitive transcranial magnetic stimulation (rTMS) applied over the supplementary motor area (SMA) in patients with stroke who had balance disorders. The study enrolled 40 participants and compared active stimulation against sham stimulation. Assessments were conducted after 10 sessions of intervention.

The primary outcome measured was the Berg Balance Scale (BBS), while secondary outcomes included the Trunk Impairment Scale (TIS), Postural Assessment Scale for Stroke Patients (PASS), active motor threshold (AMT), and motor evoked potential (MEP) amplitude. Results indicated a statistically meaningful group-by-time interaction for the BBS (F = 31.25, p = 0.001), TIS (F = 24.62, p = 0.002), and PASS (F = 13.02, p = 0.001), all showing an enhancement of balance.

In contrast, no significant group effect or group-by-time interaction was observed for active motor threshold or motor evoked potential amplitude. Safety data, including adverse events, discontinuations, and tolerability, were not reported in the study. The authors noted that the small sample size and lack of reported safety information represent key limitations.

While the results indicate that 10 Hz rTMS over the SMA can significantly enhance balance and postural control in this specific population, the evidence is limited by the small cohort and incomplete safety reporting. Clinicians should consider these findings preliminary until further research confirms efficacy and safety profiles.