IMB model-based education improved medication adherence and self-management in Parkinson's disease patients at six months versus routine careIMB Education Improved Parkinson's Care Measures at Six Months

This randomized controlled trial investigated the effectiveness of an IMB model-based health education intervention compared to routine health education alone in a cohort of 70 patients with Parkinson's disease. The study assessed outcomes at two time points: three months and six months following the intervention. No specific details regarding the setting or funding sources were reported in the available data.

Regarding primary outcomes, medication adherence improved in both the intervention and control groups at the three-month assessment. However, by six months, the intervention group demonstrated significantly higher adherence levels than the control group, with a p-value less than 0.05. At the three-month mark, the difference between groups was not statistically significant (P > 0.05). Secondary outcomes included self-health management abilities and quality of life, measured using the PDQ-39 questionnaire.

Self-health management scores increased significantly over time in both groups, but the intervention group exhibited significantly greater improvement at both three and six months (P < 0.05 for both time points). For quality of life, no significant difference was observed between groups at three months. At six months, however, the intervention group showed significantly greater improvement in PDQ-39 scores compared to the control group (P < 0.05). Absolute numbers and effect sizes were not reported for any outcome.

Safety and tolerability data were not reported; no adverse events, serious adverse events, discontinuations, or specific tolerability metrics were documented. The study did not report specific limitations, funding sources, or conflicts of interest. Given the sample size and the lack of reported adverse events, the practice relevance is currently limited to educational settings where similar interventions might be implemented, pending further research on long-term sustainability and generalizability.