Bibliometric analysis of ICU-AW literature reveals expanding global research focus on early rehabilitation and nutrition.
This study utilized a bibliometric analysis to evaluate existing literature on intensive care unit-acquired weakness (ICU-AW). The investigation included 1,449 publications from the Web of Science Core Collection and 648 publications from PubMed, involving 6,908 authors from 72 countries across 365 journals. The primary outcome assessed the temporal and spatial distribution, interconnections, and emerging trends within this research field.
The analysis identified 11 thematic clusters and 67 burst keywords through cluster analysis, burst keyword detection, and timeline mapping. These clusters encompassed diagnosis, prevention, treatment, and prognosis of ICU-AW. The data indicates a shift in research focus toward early identification, early functional rehabilitation, and nutritional support over the past two decades, with increasing contributions from East Asia and nutrition- and neuromuscular-focused journals.
Safety and adverse events were not reported as this was a bibliometric analysis of publication trends rather than a clinical trial. The study limitations include the reliance on bibliometric data rather than clinical outcomes, and the absence of reported effect sizes or p-values. However, external validation of research topics and trends in the PubMed database yielded results consistent with the preliminary analysis.
The practice relevance of these findings lies in mapping the evolution of research themes to identify emerging directions and generate hypotheses for future studies. Clinicians should note that these results describe the trajectory of scientific inquiry rather than direct patient outcomes or treatment efficacy.
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