Hospital process reengineering aimed to reduce door-to-needle time in acute ischemic stroke patients presenting within 3.5 hours.

This multicenter prospective pre-post quasi-experimental study assessed the impact of hospital process reengineering on care delivery for patients with acute ischemic stroke presenting within 3.5 hours of symptom onset. The intervention comprised pre-notification by emergency medical services, simultaneous activation of a multidisciplinary team, standardized communication protocols, and regular feedback mechanisms. This approach was compared against a pre-intervention period spanning July 1 through September 30, 2014.

The primary outcome focused on changes in door-to-needle time, while secondary outcomes included the proportion of patients receiving intravenous thrombolysis and the percentage achieving specific door-to-needle time thresholds. However, the provided evidence does not report specific numerical values for these outcomes, preventing a quantitative assessment of the intervention's impact on treatment delays or administration rates.

Safety and tolerability data were not reported, as adverse events, serious adverse events, discontinuations, and general tolerability were not documented in the available information. Furthermore, the study design is quasi-experimental, which inherently limits the ability to establish causal relationships between the process changes and observed outcomes. No specific limitations were detailed in the input data, and funding or conflict of interest information was not reported.

Given the lack of reported numerical results and the quasi-experimental nature of the design, the clinical relevance of these findings remains uncertain. Practitioners should interpret these results with caution, acknowledging that the study design and missing outcome data prevent definitive conclusions regarding the effectiveness of the reengineering strategies in this population.