Glenzocimab fails to improve outcomes in acute ischemic stroke thrombolysis
New stroke drug shows no benefit for patients treated with clot-busting therapy
This phase 2/3 randomized trial tested glenzocimab versus placebo in 421 patients with acute ischemic stroke treated by thrombolysis. The pr…
A major trial found that glenzocimab did not improve long-term disability scores for stroke patients who received standard clot-busting trea…
TMAO levels and clinical variables associated with poor outcomes in acute ischemic stroke
Gut-derived TMAO linked to poor stroke recovery outcomes
This retrospective case-control study of 213 patients with acute ischemic stroke undergoing endovascular therapy investigated associations w…
High levels of a gut-related compound may predict how well patients recover after an emergency procedure for an ischemic stroke.
A prediction model for futile reperfusion after endovascular thrombectomy in large vessel occlusion stroke
New Model Predicts Futile Stroke Reperfusion After Clot Removal
This retrospective cohort study developed a model using clinical, imaging, and laboratory markers to predict futile reperfusion after endova…
A new tool combining clinical, imaging, and lab data can predict which stroke patients may not benefit from clot removal.
Baseline psychological resilience was not independently associated with functional recovery in acute ischemic stroke patients.
Stroke Recovery Depends On Clinical Factors Not Just Mental Strength
This prospective cohort study evaluated 241 adult patients with imaging-confirmed acute ischemic stroke hospitalized for rehabilitation. Fun…
New research shows that mental resilience does not independently predict how well patients recover physically after a stroke.
Circulating biomarkers and gut microbiota profiling predict post-stroke infection in acute ischemic stroke patients.
Combined biomarkers and gut bacteria predict stroke infection risk
This prospective observational study evaluated 80 acute ischemic stroke patients admitted within 24 h of onset. Circulating biomarkers and g…
A new study suggests that mixing blood markers with gut bacteria data helps predict infections in stroke patients better than looking at jus…
Prospective cohort study validates nomograms for post-stroke cognitive impairment risk in acute ischemic stroke patients.
Stroke survivors with high cholesterol and brain shrinkage face higher cognitive risk
This prospective cohort study developed and validated standard-criteria and age-corrected nomograms to predict post-stroke cognitive impairm…
New tools predict memory and thinking problems in stroke patients based on age, cholesterol, and brain scan signs found six months after the…
Study protocol for evaluating AI-based decision support in acute ischemic stroke management
New AI System Predicts Stroke Recovery Before Treatment Starts
This study protocol describes a prospective, multicenter, observational study evaluating the VALIDATE-CDSS, an AI-based clinical decision su…
Doctors could soon use AI to predict stroke recovery chances before deciding on the best treatment plan for each patient.
Meta-analysis finds Tongxinluo capsule may improve functional outcomes in acute ischemic stroke
Tongxinluo capsule helps stroke survivors regain independence without added risk
This systematic review and meta-analysis of 4,842 patients with acute ischemic stroke found that Tongxinluo capsule was associated with impr…
A large analysis shows Tongxinluo capsule helps stroke patients stay independent and move better, with no increase in side effects compared …
Meta-analysis: Intensive BP control reduces good functional outcomes after thrombectomy
Tight blood pressure control after stroke surgery lowers disability but raises death risk
This meta-analysis of 6 randomized controlled trials in acute ischemic stroke due to large vessel occlusion after mechanical thrombectomy co…
A major analysis of six trials shows strict blood pressure limits after stroke surgery reduce disability but increase death and low blood pr…
CZTL capsule therapy study design for acute ischemic stroke patients not eligible for IVT or with early deterioration
New Stroke Pill Could Help Patients Missed by Standard Care
This randomized, double-blind, placebo-controlled, multicenter clinical study design involved 1,208 eligible patients with acute ischemic st…
A large new study is testing if a specific herbal capsule can help stroke patients who miss out on standard treatments.
Bridging IV Thrombolysis Plus EVT vs EVT Alone in Late-Window Anterior Circulation Stroke
Why Giving Two Treatments Doesn't Always Help
This retrospective analysis of a prospective registry compared bridging intravenous thrombolysis plus endovascular thrombectomy with direct …
Adding a second drug before the clot-removal procedure offers no clear benefit for most patients in the late window.
First-line suction aspiration versus combination technique for acute cerebral infarction in a multicenter trial
Imagine waking up unable to move one side of your body. This sudden loss of control is a stroke. Every minute counts when a blood vessel in the brain is blocked. Doctors race to open the vessel and save brain tissue. Time is the most important factor in recovery.
This prospective, randomized, multicenter, noninferiority, open-label trial enrolled 1136 patients with acute cerebral infarction amenable t…
Strokes are a leading cause of disability worldwide.