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Laughter yoga reduced fatigue in people with multiple sclerosis in a randomized controlled trialLaughter Yoga Cuts Fatigue And Improves Sleep For Multiple Sclerosis Patients

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Key Takeaway
Consider laughter yoga as a low-cost complementary intervention for fatigue in multiple sclerosis, pending larger validation studies.

This randomized controlled trial evaluated laughter yoga in 42 people with multiple sclerosis. The intervention group attended 12 sessions of laughter yoga, while the control group received standard care. The study setting was not reported, and funding or conflicts of interest were not reported.

Primary outcomes focused on fatigue severity. Fatigue decreased substantially in the intervention group, whereas no meaningful change was observed in the control group. The effect size for fatigue was a Cohen's d of 2.785. Secondary outcomes included sleep quality and psychological well-being. Sleep quality improved in the intervention group with a Cohen's d of 2.921 and a p-value less than 0.001. Psychological well-being increased within the intervention group, but the between-group effect at post-test was small with a Cohen's d of 0.485.

Safety data were not reported, and there were no reported adverse events, serious adverse events, discontinuations, or specific tolerability metrics. The study authors note that studies with larger samples are needed for generalizability. This low-cost and effective complementary psycho-social intervention can be used in clinical settings within the scope of nursing practice.

Imagine waking up feeling exhausted before your feet even hit the floor. This is a daily reality for many people living with multiple sclerosis. They often struggle with fatigue that no amount of rest can fix. Sleep becomes a battle rather than a relief.

But there is a new way to fight back. A recent study shows that laughter yoga might be the answer. This simple practice brings joy and relaxation to those who need it most.

Multiple sclerosis affects the nervous system and causes a wide range of symptoms. Fatigue is one of the most common and frustrating problems. It can stop people from working, playing with family, or enjoying their hobbies.

Current treatments often focus on slowing disease progression. They do not always help with the day-to-day feeling of being drained. Patients need tools to manage their energy and get restful sleep.

The Old Way Vs New Way

Doctors have long prescribed medication for sleep and energy issues. These drugs can cause drowsiness or other side effects. Patients often feel they must choose between feeling better and avoiding new problems.

But here is the twist. This research suggests a non-drug approach works very well. Laughter yoga is a gentle activity that does not require heavy exercise. It fits easily into a busy schedule.

A Switch That Burns Fatigue

Think of your body like a factory with a traffic jam. Stress and tension block the flow of energy. Laughter acts like a switch that clears the jam. It signals the brain to relax and let go of tension.

When you laugh, your body releases endorphins. These are natural chemicals that make you feel good. They also help lower stress hormones that keep you awake and tired. This simple biological change helps you rest better at night.

Researchers tested this idea on forty-two people with multiple sclerosis. They split the group into two teams. One team practiced laughter yoga for twelve sessions. The other team received standard care but no special training.

The results were clear and impressive. The group that practiced laughter yoga felt much less fatigued. Their scores on fatigue scales dropped significantly compared to the control group. Sleep quality also improved dramatically in the laughter group.

But There Is A Catch

The study showed big gains for fatigue and sleep. However, the improvement in psychological well-being was smaller between the two groups. This means the practice helped individuals feel better, but the group difference was not as large.

This does not mean the treatment is a magic cure for everyone. It is a helpful tool that works best as part of a larger plan.

What Experts Say

Experts in nursing and psychology see this as a valuable addition to care. It fits well into nursing practice because it is safe and easy to teach. Nurses can guide patients through simple breathing and laughing exercises during visits.

This approach complements other treatments rather than replacing them. It gives patients a sense of control over their symptoms. Feeling active and engaged helps improve overall mood and outlook.

You can talk to your doctor about trying laughter yoga. It is a low-cost option that requires no special equipment. You can practice alone or with a small group of friends.

Start with short sessions to see how your body reacts. Listen to your energy levels and sleep patterns. If you feel better, keep going. If not, adjust the routine to fit your needs.

The Limitations

This study had a small group of forty-two people. The results are promising, but more research is needed to confirm them. We need to know if this works for all types of multiple sclerosis. Larger studies will help doctors decide who should use this method.

More trials are planned to test this method on larger groups. Researchers want to see if it works for other conditions too. Until then, it remains an exciting option for managing symptoms.

The future of care includes more options like this. It gives patients hope and practical tools. Laughter yoga shows that joy can be medicine. It reminds us that small changes can lead to big improvements in daily life.

Study Details

Study typeRct
EvidenceLevel 2
PublishedMay 2026
View Original Abstract ↓
BACKGROUND AND PURPOSE: Symptoms such as fatigue, sleep disturbances, and impaired psychological well-being are common in individuals Multiple Sclerosis (MS). However, studies on the use of laughter yoga, a non-invasive intervention method, are very limited in the literature. The aim of this study was to evaluate the effects of laughter yoga on fatigue, sleep quality and psychological well-being in individuals with MS. MATERIALS AND METHODS: In this randomized controlled trial, 42 people with MS were randomly assigned to intervention or control group. The intervention group received a total of 12 sessions of laughter yoga. Descriptive Information Form, Fatigue Severity Scale (FSS), Pittsburgh Sleep Quality Index (PSQI) and Psychological Well-Being Scale (PWBS) were used to collect data. RESULTS: Laughter yoga was associated with improvements in fatigue and sleep outcomes. Fatigue severity decreased substantially in the intervention group (Cohen's d = 2.785), with no meaningful change observed in the control group. Sleep quality improved in the intervention group, as indicated by reduced Pittsburgh Sleep Quality Index scores (p < 0.001, d = 2.921). Psychological well-being increased within the intervention group (d = -1.505); however, the between-group effect at post-test was small (d = 0.485). CONCLUSION: Laughter yoga showed statistically significant results in terms of decreasing fatigue level, increasing sleep quality and psychological well-being in individuals with MS. The findings suggest that laughter yoga is a low-cost and effective complementary psycho-social intervention that can be used in clinical settings within the scope of nursing practice. This intervention offers an evidence-based approach that can be integrated into nursing care to manage fatigue and sleep problems and improve psychological well-being in individuals with MS. For the generalizability of the effects of laughter yoga, studies with larger samples are needed.
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