Observational study finds 16% COVID-19 vaccination coverage among pregnant people in U.S.

An observational study using CDC Vaccine Safety Datalink data examined COVID-19 vaccination coverage among pregnant people across eight U.S. integrated healthcare organizations. The study assessed receipt of at least one dose of a COVID-19 vaccine during pregnancy, with no specific comparator group reported. As of May 2021, overall vaccination coverage was 16%. Coverage varied significantly by race/ethnicity and age: it was lowest among Hispanic people (12%), non-Hispanic Black people (6%), and people aged 18-24 years (6%). Coverage was highest among non-Hispanic Asian people (25%) and people aged 35-49 years (23%). The study did not report data on adverse events, serious adverse events, discontinuations, or tolerability. Key limitations include the lack of reported sample size, follow-up duration, and statistical measures like p-values or confidence intervals. The analysis is purely descriptive and does not establish causality or assess the safety or efficacy of vaccination during pregnancy. Its practice relevance is limited to providing a snapshot of early vaccination uptake and identifying demographic groups with lower coverage, which may inform public health outreach efforts.