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Observational study finds 16% COVID-19 vaccination coverage among pregnant people in U.SHow many pregnant people got COVID shots? Early data shows gaps

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Key Takeaway
Note low and variable COVID-19 vaccination coverage among pregnant people in this descriptive U.S. study.

An observational study using CDC Vaccine Safety Datalink data examined COVID-19 vaccination coverage among pregnant people across eight U.S. integrated healthcare organizations. The study assessed receipt of at least one dose of a COVID-19 vaccine during pregnancy, with no specific comparator group reported. As of May 2021, overall vaccination coverage was 16%. Coverage varied significantly by race/ethnicity and age: it was lowest among Hispanic people (12%), non-Hispanic Black people (6%), and people aged 18-24 years (6%). Coverage was highest among non-Hispanic Asian people (25%) and people aged 35-49 years (23%). The study did not report data on adverse events, serious adverse events, discontinuations, or tolerability. Key limitations include the lack of reported sample size, follow-up duration, and statistical measures like p-values or confidence intervals. The analysis is purely descriptive and does not establish causality or assess the safety or efficacy of vaccination during pregnancy. Its practice relevance is limited to providing a snapshot of early vaccination uptake and identifying demographic groups with lower coverage, which may inform public health outreach efforts.

When COVID-19 vaccines first became available, a big question was whether pregnant people would get them. An early look at data from eight major U.S. health systems found that by May 2021, only 16% of pregnant people had received at least one dose during their pregnancy. The study, which used records from the CDC's Vaccine Safety Datalink, shows this overall number hides wide gaps. Vaccination coverage was lowest among Hispanic people (12%), non-Hispanic Black people (6%), and people aged 18-24 years (6%). It was highest among non-Hispanic Asian people (25%) and people aged 35-49 years (23%). This is just a snapshot of who got vaccinated in the early months of the rollout. It's an observational study, meaning it simply reports what happened without trying to explain the reasons behind these choices. The data doesn't assess whether the vaccines were safe or effective for this group, and it doesn't tell us what happened after May 2021. It simply gives us a first look at who was getting the shot and where significant disparities existed.

What this means for you:
Early COVID vaccine uptake in pregnancy was low, with clear gaps by age and race.

Study Details

EvidenceLevel 5
PublishedJun 2021
View Original Abstract ↓
As of May 2021, 16% of pregnant people identified in CDC's Vaccine Safety Datalink had received ≥1 dose of a COVID-19 vaccine during pregnancy in the U.S. Vaccination was lowest among Hispanic people (12%), non-Hispanic Black people (6%), and people aged 18-24 years (6%), and highest among non-Hispanic Asian people (25%) and people aged 35-49 years (23%).
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