Clozapine Use Linked to Higher SARS-CoV-2 Infection Risk in Severe Mental Disorders
Clozapine users faced higher risk of severe COVID-19 in large study
A meta-analysis of 155,945 outpatients with severe mental disorders found that clozapine users had a higher rate of SARS-CoV-2 infection com…
A massive analysis of over 155,000 people found that those taking clozapine had higher rates of infection and worse outcomes from COVID-19.
Inactivated SARS-CoV-2 vaccine dosing schedules and antibody responses in adults aged 60 to 80 years
Older adults get better protection with the right vaccine booster timing
This prospective cohort study of 450 adults aged 60 to 80 years in China examined three inactivated SARS-CoV-2 vaccine dosing schedules. The…
New data shows older adults get the best protection when they receive specific vaccine boosters at the right time.
Survey finds physicians show stronger intergroup bias than public on vaccines
Doctors Show Strong Bias Against Vaccine-Hesitant Patients
This review of an online survey in Japan involving 492 physicians and 5,252 members of the general public found that physicians exhibited hi…
Doctors often see themselves as targets of vaccine anger, but new data shows they also hold strong bias against patients who question vaccin…
Metformin, fluvoxamine, or ivermectin for non-hospitalized COVID-19 adults in a Phase 3 trial
Metformin Cuts Long Covid Risk by 40%
This randomized controlled trial in 1323 non-hospitalized adults with SARS-CoV-2 infection evaluated metformin, fluvoxamine, or ivermectin v…
A common diabetes pill taken early in Covid infection cuts the odds of developing long-term symptoms by 40%, offering new hope for millions.
Systematic review finds no benefit of higher-dose fluvoxamine for preventing deterioration in mild-moderate COVID-19
Higher-Dose Fluvoxamine Shows No Clear Benefit for COVID-19, New Analysis Finds
This systematic review and meta-analysis evaluated higher-dose fluvoxamine (2 x 100 mg/day) versus placebo in adults with mild-to-moderate C…
This new analysis suggests that higher doses of fluvoxamine, once thought to help early COVID-19, likely don’t prevent the disease from prog…
Scoping Review Assesses Active Surveillance Systems for Antivirals and Corticosteroids in COVID-19
How Hospitals Tracked COVID Drug Risks in Real Time
This scoping review analyzed 15 publications from 9,183 literature records to evaluate active surveillance systems for COVID-19 medications …
This study shows how doctors tracked COVID drug safety in real time, helping patients get safer care during a crisis.
Remdesivir reduces COVID-19 hospitalization or death risk in high-risk outpatients
Remdesivir may cut hospitalization risk for high-risk COVID outpatients
This Bayesian reanalysis of a Phase 3 RCT in high-risk outpatients with COVID-19 found a posterior median hazard ratio of 0.13 for COVID-19-…
A reanalysis of trial data suggests remdesivir sharply lowers the chance of hospitalization or death for high-risk COVID patients treated at…
Hospital stay and mortality vary by pandemic wave and vaccination status in severe COVID-19.
More Older Patients Now Get Severe COVID
This retrospective descriptive study analyzed 1,425 patients with severe COVID-19 across pandemic waves from March 2020 to November 2022. Ho…
It used to be younger men filling ICU beds during the first wave of the pandemic.
Preclinical modeling study on COVID-19 and Ebola epidemic dynamics and interventions
Cities Spread Disease Faster — Here’s What Helps
This is a preclinical modeling study using a UK-based spatial metapopulation SEIR framework to simulate COVID-19 and Ebola outbreaks. The au…
This new tool could help leaders slow epidemics before they explode.
COVID-19 infection associated with lower live birth rates in fresh embryo transfer cycles.
COVID-19 May Lower IVF Success Rates, New Data Shows
This retrospective cohort study of 1,025 fresh embryo transfer cycles found that COVID-19 infection was associated with a lower live birth r…
COVID-19 infection before IVF egg retrieval is linked to a lower chance of live birth and a higher risk of miscarriage, according to a new s…
mRNA-1283 and BNT162b2 COVID-19 vaccines show protective effectiveness in adults aged 65 and older.
New Vaccine Cuts Hospital Risk for Seniors by Nearly 60%
This observational cohort study in U.S. adults aged >=65 years found mRNA-1283 had higher adjusted vaccine effectiveness (aVE) for COVID-19 …
A new 2025–2026 COVID vaccine slashes hospital risk for seniors by nearly 60%, offering stronger protection when aging immune systems need i…
Retrospective cohort finds COVID-19 infection linked to proteinuria progression in type 2 diabetes
Does COVID-19 worsen kidney issues in people with diabetes?
A retrospective cohort study of 688 patients with type 2 diabetes and COVID-19 versus 502 pre-pandemic uninfected patients with type 2 diabe…
Type 2 diabetes patients fear COVID-19 could worsen kidney stress, raising questions about whether weight or obesity accelerates the risk.