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Mandala painting and music therapies improve quality of life and psychological well-being in cancer survivorsArt and music therapies improve well-being for cancer survivors

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Key Takeaway
Consider mandala painting and music therapy to improve quality of life and manage fatigue in cancer survivors.

This network meta-analysis evaluated the efficacy of various art therapies, including mandala painting and music therapy, for cancer survivors. The analysis included a total sample size of 2,542 participants to assess outcomes such as depression, quality of life, fatigue, anxiety, and pain.

Mandala painting therapy was associated with statistically significant improvements in both quality of life and the alleviation of depression. Music therapy demonstrated superior efficacy for fatigue reduction compared to routine care (SMD = -5.83; 95% CrI: -6.65, -5.02). While music therapy achieved high SUCRA rankings for anxiety relief (67.4%) and pain relief (69.0%), pairwise comparisons did not reach statistical significance for these specific outcomes.

The authors note several limitations, including the absence of closed loops in the evidence network, substantial clinical heterogeneity, and potential publication bias. These factors necessitate a cautious interpretation of SUCRA-based rankings. Clinical application is supported by the finding that mandala painting and music therapy may improve psychological well-being, though results should be viewed with caution due to the inherent limitations of the meta-analysis.

How this fits prior evidence

This network meta-analysis addresses a gap in nonpharmacological supportive care for cancer survivors. While previous coverage highlighted multicomponent nonpharmacological interventions to reduce delirium incidence in adult patients with cancer, this study specifically evaluates art therapies like mandala painting and music therapy to improve psychological well-being and quality of life.

Living with the aftermath of cancer brings heavy emotional burdens. Many survivors struggle with persistent feelings of exhaustion, anxiety, and a diminished sense of well-being. New research looking at 2,542 survivors suggests that creative therapies like music and mandala painting can offer meaningful support beyond standard medical care.

Specifically, the study found that mandala painting therapy significantly helped reduce depression and improved overall quality of life for those who participated. Music therapy also showed great promise in fighting fatigue, ranking very highly in its category. While music therapy also showed high rankings for relieving anxiety and pain, these specific results were not statistically significant when compared directly to other options.

It is important to note that the evidence comes from a network analysis, which means researchers are still piecing together the full picture. Because of differences in how studies were conducted and potential biases in published reports, these findings should be viewed as promising starting points rather than definitive proof. Talk with your healthcare team about how these creative therapies might fit into your personal recovery plan.

What this means for you:
Mandala painting and music therapy can help cancer survivors manage depression, fatigue, and improve quality of life.

Common questions

Can mandala painting help with depression after cancer?

Yes, the study found that mandala painting therapy showed statistically significant success in helping to alleviate depression among cancer survivors. It also significantly improved their overall quality of life.

How does music therapy affect fatigue and pain?

Music therapy was shown to be superior to routine care for reducing fatigue. While it also showed high rankings for relieving anxiety and pain, these specific results did not show statistically significant differences in direct comparisons.

Is this research definitive for all patients?

The findings are promising but should be viewed with some caution. The study noted issues like variations between different studies and potential publication bias, meaning these results are an association rather than a guaranteed outcome for every individual.

Study Details

Study typeMeta analysis
EvidenceLevel 1
PublishedJul 2026
View Original Abstract ↓
Art therapy has gained increasing attention as an adjunctive intervention for cancer patients. This study sought to conduct the first network meta-analysis (NMA) to evaluate the effects of various art therapies on the psychological well-being and quality of life in cancer survivors, rank various interventions by efficacy, and provide evidence-based guidance for clinical practice. Web of Science, PubMed, Embase, and the Cochrane Library, were systematically searched for studies published up to September 3, 2025. Eligible studies were selected according to predefined criteria, and data were independently extracted by two researchers. Heterogeneity was assessed using the I² statistic, and fixed- or random-effects models were applied accordingly. A Bayesian NMA was conducted to compare interventions and rank their efficacy using the surface under the cumulative ranking curve (SUCRA). Publication bias was assessed using comparison-adjusted funnel plots and Egger’s test. Network meta-regression was performed for outcomes with high heterogeneity. Analyses were conducted using R Studio v4.5.2 and STATA v15.0. Twenty-eight studies involving 2,542 cancer survivors were included. The NMA demonstrated that mandala painting therapy exhibited statistically significant efficacy in alleviating depression and enhancing quality of life. Regarding fatigue reduction, music therapy was superior to routine care (standardized mean difference [SMD] = -5.83, 95% credible interval [CrI]: -6.65, -5.02) and had the highest SUCRA ranking (96.4%). In terms of anxiety and pain relief, although music therapy had high SUCRA rankings (67.4% and 69.0%, respectively), pairwise comparisons did not show statistically significant differences. Mandala art therapy and music therapy may improve psychological well-being and quality of life among cancer survivors. However, because of the absence of closed loops in the evidence network, substantial clinical heterogeneity, and potential publication bias, SUCRA-based rankings should be interpreted cautiously. Further high-quality, multi-arm, standardized randomized controlled trials with lower risk of bias are needed to confirm these findings. https://www.crd.york.ac.uk/PROSPERO/, identifier CRD420251149102
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