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CVC catheters reduce puncture site leakage versus CPNB catheters for fascia iliaca block in elderly hip fracture surgery

CVC catheters reduce puncture site leakage versus CPNB catheters for fascia iliaca block in elderly …
Photo by Navy Medicine / Unsplash
Key Takeaway
Note: CVC catheters linked to less leakage than CPNB catheters, but no difference in pain relief was found.

This randomized controlled trial enrolled 64 elderly patients (aged 60-75 years, ASA class I-III) scheduled for intramedullary nail fixation of femoral intertrochanteric fractures. It compared two catheter types for continuous fascia iliaca compartment block analgesia: single-lumen central venous catheters (CVCs) versus continuous peripheral nerve block (CPNB) catheters. The primary outcome was the incidence and extent of puncture site leakage assessed 48 hours postoperatively.

The main results showed a significant reduction in leakage with CVCs. The incidence of puncture site leakage was 16.1% in the CVC group compared to 96.8% in the CPNB group (P < .001). The mean leakage area was also significantly smaller in the CVC group (0.61 ± 0.46 cm) versus the CPNB group (19.30 ± 4.64 cm, P < .001). However, the study found no significant differences in postoperative analgesic efficacy, as measured by visual analog scale pain scores at 6, 24, and 48 hours, or in other secondary outcomes including block success rate.

Safety and tolerability data were not reported. Key limitations include the short 48-hour follow-up period and the lack of reported data on analgesic efficacy differences. The study did not find that reduced leakage translated to improved pain control. For practice, this evidence suggests CVCs may be associated with less local anesthetic leakage at the catheter site, but clinicians should note this did not correlate with better analgesia in this short-term study.

Study Details

Study typeRct
EvidenceLevel 2
Follow-up900.0 mo
PublishedApr 2026
View Original Abstract ↓
PURPOSE: To compare the incidence of puncture site leakage and postoperative analgesia between single-lumen central venous catheter (CVC) and continuous peripheral nerve block (CPNB) catheter for continuous fascia iliaca compartment block analgesia in elderly patients with hip fractures. DESIGN: A prospective, randomized, parallel-group controlled trial. METHODS: Sixty-four elderly participants (aged 60-75 years, American Society of Anesthesiologists class I-III) scheduled for intramedullary nail internal fixation (PFNA) of femoral intertrochanteric fractures were randomly allocated to two groups: CVC group and Continuous Peripheral Nerver Block catheter (CPNB group). In all patients, the continuous block catheter was inserted into the fascia iliaca compartment above the inguinal ligament under the guidance of ultrasound, and the postoperative analgesic pump was used. Patients in both groups underwent treatment with an ultrasound-guided in-plane approach to the fascia iliaca space via the inguinal ligament, along with the use of a postoperative analgesia pump. The degree of leakage from the two types of catheters was assessed 48 hours postoperatively, with the severity of leakage at the puncture site being qualitatively and quantitatively evaluated based on the color change of a medical-surgical film containing iodophor Secondary outcomes included the time required for puncture and catheterization, visual analog scale pain scores at 6, 24, and 48 hours postoperatively, the success rate of lower limb nerve block, and the incidence of adverse reactions to nerve block. FINDINGS: In comparison with the CPNB group, the CVC group exhibited a significantly lower incidence of puncture site leakage (96.8% vs 16.1%, P < .001) and a smaller leakage area (19.30 ± 4.64 cm vs 0.61 ± 0.46 cm, P < .001). However, no significant differences were observed in postoperative analgesic efficacy or other secondary outcomes between the two groups. CONCLUSIONS: In elderly patients with hip fractures, using CVCs for postoperative analgesia is associated with a reduced incidence and extent of leakage at the puncture site during continuous fascia iliaca compartment block.
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