This review looked at how well different animals represent human nose problems. Scientists studied mice, sheep, and pigs to see which ones act like people when getting sick. The goal was to find the best way to test new medicines before trying them on humans.
Mice are very common in labs because they are small and easy to care for. However, their nose structure is very different from ours. This means medicines that work in mice might not work in people. Sheep and pigs have noses that look more like humans, but they are harder to study.
The study shows we need to move away from easy models that do not match reality. Using animals that look and act like humans will help doctors create better treatments. This change will make sure new drugs work for patients instead of just for animals.