This narrative review looks at extracellular vesicles as potential biomarkers. The authors examine how these tiny particles might help detect cancer, neurological disorders, and cardiovascular diseases. No specific patients or sample sizes were reported because this is a review of existing literature rather than a new clinical trial. The text does not include data on safety or side effects.
The main takeaway is that while the idea is promising, significant technical challenges exist. Current methods for isolating, characterizing, and detecting these vesicles face bottlenecks. Additionally, there are ongoing challenges related to standardizing these processes for clinical use.
Readers should understand that this is a narrative review, not a practice-changing study. The evidence is limited by the lack of standardized methods and the early stage of this research area. Until these technical issues are resolved, these biomarkers cannot be used in routine care.