This large review looked at how gut-friendly supplements affect kids with type 1 diabetes. Researchers checked 808 young people who took oral probiotics, prebiotics, or a mix of both. The goal was to see if these treatments could help control blood sugar better than usual care.
The results showed clear improvements in blood sugar control. Participants who took these supplements had lower A1C levels and lower fasting blood glucose. This means their bodies processed sugar more effectively over time. However, the amount of insulin needed did not change much for most children.
Other important health markers did not improve significantly. The study could not measure changes in immune health or gut bacteria because the reports were too different. Safety was generally good, with no serious side effects reported for the participants.
Experts say these findings are promising but not enough to change medical advice yet. Different studies used different types of supplements and doses, making it hard to compare results. Future research must focus on finding the right formula and amount for young patients.