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Review explores monkey intestinal disease as possible model for human IBS

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Review explores monkey intestinal disease as possible model for human IBS
Photo by Daniel Pell / Unsplash

Scientists reviewed research about a serious intestinal condition called chronic enterocolitis (CE) in rhesus macaques, a type of monkey. This condition causes ongoing diarrhea and severe weight loss, and it leads to euthanasia in up to 25% of affected adult monkeys in research colonies. The review explores whether this illness could be a naturally occurring model for a human condition called post-infectious irritable bowel syndrome (PI-IBS), which affects over one-third of people after a bad stomach infection.

The review notes there is some evidence that the monkey syndrome might happen after an infection, similar to how PI-IBS develops in humans. If this link is proven, studying the monkeys could help researchers understand the human disease better. However, the review itself does not provide new data or prove this connection.

It is important to be cautious because this is a review paper summarizing other studies, not a new experiment. The exact cause of the monkey disease is still unknown, and efforts to manage it have had mixed results. For now, this work highlights a potential area for future research, but it does not offer immediate new treatments or a confirmed model for human IBS.

What this means for you:
A review suggests a monkey disease may model human IBS, but this is not yet proven and is for research purposes only.
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