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Irritable Bowel Syndrome

Part of Colonic Diseases

12 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Irritable Bowel Syndrome

51 trials tracked for Irritable Bowel Syndrome: 12 in phase 3 or 4 and 4 with published results. The most-cited published study has 325 citations.

51Trials tracked

12Phase 3 & 4

0Recruiting

4With published results

Phase distribution

Phase 4 7 Phase 3 5 Phase 2 18 Phase 1 1 Other / NA 20

Phase 3 Efficacy, Safety, and Tolerability of Eluxadoline in the Treatment of Participants With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-d) Completed · 325 cited
Phase 3 Efficacy, Safety, and Tolerability of Eluxadoline in the Treatment of Participants With Diarrhea-Predominant Irritable Bowel Syndrome (IBS-d) Completed · 325 cited
Phase 3 Long Term Safety Study of Plecanatide Completed · 9 cited
Phase 4 A Longitudinal Study to Identify IBS Phenotypes Using Fecal Microbiota and Hydrogen Breath Testing Completed
Phase 4 Open Trial of Duloxetine in Outpatients With Irritable Bowel Syndrome Symptoms and Co-Morbid Major Depression Completed
Phase 4 Pregabalin on Colonic Motor and Sensory Function in Constipation Predominant Irritable Bowel Syndrome Completed

Show 44 more trials

Phase 4 An Open Label Trial of Duloxetine in the Treatment of Irritable Bowel Syndrome and Comorbid Generalized Anxiety Disorder Completed
Phase 4 Effectiveness of On-demand Meteospasmyl® Use in Irritable Bowel Syndrome (IBS) Completed
Phase 4 An Open-Label Trial of Duloxetine for the Treatment of Irritable Bowel Syndrome Completed
Phase 4 Effect of Lactobacillus Plantarum 299v on Symptoms of Irritable Bowel Syndrome Completed
Phase 3 The Effect of Long-Acting Mesalamine on Post-Infective Irritable Bowel Syndrome- A Pilot Study Completed
Phase 3 Efficacy and Safety of Lubiprostone in Patients With Irritable Bowel Syndrome With Constipation Completed
Phase 2 Study of LX1031 in Subjects With Non-Constipating Irritable Bowel Syndrome Completed
Phase 2 A Trial for New Treatment of Adult Participants With Irritable Bowel Syndrome Completed
Phase 2 Efficacy, Safety, and Tolerability of JNJ-27018966 (Eluxadoline) in the Treatment of Irritable Bowel Syndrome With Diarrhea Completed
Phase 2 Ibodutant for Relief of Irritable Bowel Syndrome (IRIS) Completed
Phase 2 SH-DS01 on Fecal Metagenomic Stability Completed
Phase 2 Citalopram in Irritable Bowel Syndrome Completed
Phase 2 Randomized Placebo Controlled Efficacy And Safety Study Investigating GW876008 In Patients With Irritable Bowel Syndrome Completed
Phase 2 A Placebo-Controlled Trial of St. John's Wort for Irritable Bowel Syndrome Completed
Phase 2 Comparing a 182mg Colon-targeted-delivery Peppermint Oil Capsule (Tempocol-ColoPulse®) and a 182mg Enteric-coated Peppermint Oil Capsule (Tempocol®), a Pharmacokinetic Study Completed
Phase 2 Efficacy of Mesalamine in Diarrhea-predominant Irritable Bowel Syndrome (dIBS) Completed
Phase 2 Comparison of Rimegepant and Placebo for Pain in IBS Completed
Phase 2 Effect of a Cannabinoid Agonist on Colonic Sensory Functions in Patients With Irritable Bowel Syndrome Completed
Phase 2 Fecal Microbiota Transplantation for the Treatment of Diarrhea-Predominant Irritable Bowel Syndrome Completed
Phase 2 Does Welchol (Colesevelam Hydrochloride) Improve Colonic Transit in Diarrhea-predominant Irritable Bowel Syndrome (D-IBS)? Completed
Phase 2 Study to Evaluate the Efficacy and Safety of Vibegron Administered Orally for 12 Weeks to Women With Irritable Bowel Syndrome Completed
Phase 2 Effect of Cannabinoid Agonist on Gastrointestinal and Colonic Motor Functions in Patients With Irritable Bowel Syndrome (IBS) Completed
Phase 2 A Placebo-Controlled Trial of Pregabalin (Lyrica) for Irritable Bowel Syndrome Completed
Phase 2 Vestibulodynia: Understanding Pathophysiology and Determining Appropriate Treatments Completed
Phase 1 A Phase 1, First Time in Human (FTIH) Study to Evaluate GSK3352589, a REarranged During Transfection (RET) Growth Factor Receptor Tyrosine Kinase Inhibitor, in Healthy Volunteers Completed
N/A Effects of Low FODMAP Diet on Colonic Epithelial Physiology in Diarrhea-predominant Irritable Bowel Syndrome Completed
N/A Irritable Bowel Syndrome Hypnotherapy Completed
N/A Efficacy and Safety of IBS Digital Behavioral Treatment Completed
N/A Acceptability and Efficacy of the Zemedy App for Irritable Bowel Syndrome Completed
N/A Evaluating the Efficacy of the Mediterranean Diet to the Low- Fermentable, Oligosaccharides, Disaccharides, Monosaccharides, and Polyols (FODMAP) Diet in Treating Irritable Bowel Syndrome(IBS) Completed
N/A Does Improving Vagal Tone Increase Mitochondrial Bioenergetics Completed
N/A Advanced Metagenomic Analysis of Human Colonic Microbiota in Patients With Chronic GI Disorders Completed
N/A Effects of Lubiprostone on Gastrointestinal Transit & pH in Irritable Bowel Syndrome (IBS) With Constipation Completed
N/A Chronic Gastrointestinal Sequelae of an Acute Outbreak of Bacterial Gastroenteritis in Walkerton Ontario Completed
N/A A Randomized, Single Centre, Double-blind, Parallel, Sham-controlled Pilot Study Using gammaCore®-G Completed
N/A Mindfulness-Based Stress Reduction for Bowel Symptoms: Collection of Pilot Survey Data Completed
N/A Peer Mentorship: An Intervention To Promote Effective Pain Self-Management In Adolescents Completed
N/A Gulf War Digestive Health Study Completed
N/A Effects of Open-label vs Double-blind Treatment in IBS Completed
N/A Self Administered Cognitive Behavior Therapy for Irritable Bowel Syndrome Completed
N/A The Value of Bio-electrical Impedance Analysis in Irritable Bowel Syndrome Completed
N/A Percutaneous Electrical Nerve Field Stimulation for Adults With Irritable Bowel Syndrome Completed
N/A Biomarkers for Intestinal Permeability in Patients With Constipation Completed
N/A Efficacy of Open Label Placebo in Children With FGIDs Completed

Showing the 50 most-cited and recently-updated of 51 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

Questions about Irritable Bowel Syndrome

Are there specific risk factors for irritable bowel syndrome in Bangladeshi students?

Yes, in Bangladeshi students, the strongest risk factors for IBS are psychological distress, elevated BMI, and academic dissatisfaction, according to a machine-learning analysis.

Full answer →

What is the Chinese version of the IBS symptom severity scale?

The Chinese version of the IBS Symptom Severity Scale (IBS-SSS-C) was developed through translation and cross-cultural adaptation, and has been validated for assessing IBS severity in Chinese populations.

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Can acupuncture really help my irritable bowel syndrome symptoms?

Yes, acupuncture can help relieve IBS symptoms, especially abdominal pain and diarrhea, based on recent clinical trials showing significant improvement over sham acupuncture.

Full answer →