This article reviews the emerging use of vaginal microbiota transplantation (VMT) for women with dysbiosis of the female genital tract microbiota. The goal is to provide a robust theoretical foundation and practical guidance for the scientifically sound promotion and standardized application of this procedure. The review compares VMT against conventional antimicrobial therapies to explore its potential benefits for restoring healthy microbiota and improving sexual quality of life.
The study notes several significant limitations that must be considered. These include a lack of standardized donor screening criteria and variability in procedural protocols, which makes it difficult to compare different approaches. Furthermore, there is insufficient long-term safety data available, and ethical and regulatory considerations are still evolving in this field. Because these issues have not been fully resolved, the current evidence does not yet support widespread clinical adoption.
Readers should understand that this review offers guidance for future investigation rather than immediate practice-changing recommendations. While VMT shows promise, the absence of standardized methods and long-term safety information means that more research is needed before it can be confidently recommended. Patients should wait for further studies that address these gaps before considering this treatment option.