Human milk fortifiers for preterm infants: a narrative review of current and investigational optionsNew Fortifiers May Help Preterm Infants with Growth Restriction

This is a narrative review that surveys current and novel or investigational human milk fortifiers for preterm infants, particularly those with extrauterine growth restriction. The authors describe the rationale for fortification and the types of fortifiers in use, including those under investigation. No pooled effect sizes or quantitative outcomes are reported; the review is descriptive in nature.

The review highlights that human milk fortifiers are commonly used to support growth in preterm infants, but it does not provide comparative efficacy data or specific outcome measurements. The authors note that this is a narrative review, which limits the strength of conclusions. No safety data, adverse events, or discontinuation rates are reported.

For clinicians, this review offers a broad overview of available and emerging fortifier options but does not provide evidence-based recommendations. The lack of clinical trial data means that practice decisions should rely on existing guidelines and primary studies. The review underscores the need for more rigorous research to guide fortifier selection.