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OPEP device added to chest physiotherapy improves adherence but not clinical outcomes in children with bronchiectasisAdding a breathing device to chest physiotherapy improved adherence but not clinical outcomes in children with bronchiectasis

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Key Takeaway
Consider OPEP for adherence support in pediatric bronchiectasis, not for added clinical benefit.

This randomized trial enrolled 42 children with non-cystic fibrosis bronchiectasis to compare an 8-week multicomponent chest physiotherapy program alone versus the same program plus an oscillatory positive expiratory pressure device. The primary outcomes were exercise capacity and dynamic ventilatory responses.

Both groups showed significant improvement in 6-minute walk test distance, change in inspiratory capacity during exertion, lowest SpO2, time spent with a drop of ≥4% in SpO2, FVC%, FEV1%, and PEF%. However, there was no significant difference between groups for any of these clinical outcomes. The CPT + OPEP group had significantly higher program adherence (85 ± 15% vs 74 ± 18%, p < 0.05).

Safety and tolerability data were not reported. Key limitations include the small sample size, short 8-week follow-up, lack of reported effect sizes and confidence intervals, and absence of data on long-term outcomes or clinical events like exacerbations. Funding and conflicts of interest were not reported.

For practice, this single trial suggests that a structured chest physiotherapy program may benefit children with bronchiectasis. The decision to add an OPEP device may be individualized to address engagement or feasibility rather than to achieve further clinical benefit, though this requires confirmation in larger, longer-term studies.

Researchers conducted an 8-week study with 42 children who have bronchiectasis, a lung condition that causes a persistent cough and mucus buildup. They wanted to see if adding a handheld breathing device, called an oscillatory positive expiratory pressure (OPEP) device, to a standard chest physiotherapy (CPT) program would help children breathe better during exercise. The CPT program included exercises to clear mucus and improve lung function.

All children did a multicomponent CPT program. Half of them also used the OPEP device. After 8 weeks, both groups of children showed improvements in how far they could walk in 6 minutes and in several breathing measurements taken during exercise. However, there was no significant difference in these improvements between the group that used the extra device and the group that did not. The main finding was that children who had the OPEP device were slightly better at sticking to their daily physiotherapy routine.

The study was quite small and only lasted for 8 weeks, so we don't know if these results would hold up over a longer period or in a larger group of children. The researchers did not report on safety, side effects, or whether the program reduced lung infections (exacerbations). The takeaway is that a structured home physiotherapy program can be helpful for children with bronchiectasis. Adding a specific device might help some children follow the program more consistently, but based on this study, it does not seem to provide extra improvement in exercise capacity or breathing measures.

What this means for you:
A home physiotherapy program helped children with bronchiectasis. Adding a specific device improved adherence but not clinical outcomes in this small, short study.

Study Details

Study typeRct
EvidenceLevel 2
Follow-up1.8 mo
PublishedApr 2026
View Original Abstract ↓
BACKGROUND: Airway clearance is major part of care for children with bronchiectasis (BE) and oscillatory positive pressure (OPEP) devices are widely used, yet their added value beyond a multicomponent chest physiotherapy (CPT) program remains unclear and device access often entails out of pocket costs. Aim of this study was to evaluate whether adding an OPEP device to a multicomponent CPT program provides additional benefits in exercise capacity and dynamic ventilatory responses in children with BE. METHODS: A randomized trial involving 42 children with non-cystic fibrosis BE was conducted. Children were allocated to either CPT or CPT + OPEP group. Both groups trained at home twice daily for 8 weeks. 6-min walk test (6MWT) with Spiropalm® device, spirometry, quadriceps strength measurement and Leicester Cough Questionnaire (LCQ) were applied at baseline and after training. RESULTS: 6MWT distance, change in inspiratory capacity during exertion (ΔIC), lowest SpO, the time spent with a drop of ≥ %4 in SpO [T (dSpO ≥ %4)], FVC%, FEV%, PEF%, significantly improved in both groups, with no between-groups difference. Program adherence (%) was significantly higher in CPT + OPEP group (85 ± 15) compared to CPT group (74 ± 18) (p < 0.05). CONCLUSION: In children with BE, a multicomponent CPT program improved exercise capacity, dynamic ventilatory responses and spirometry, while adding an OPEP device primarily increased adherence and conferred no additional benefit. The decision to add an OPEP device may be individualized to address engagement or feasibility rather than further clinical benefit. TRIAL REGISTRATION: The study was prospectively registered to ClinicalTrials. gov on September 1, 2021, under the registration number NCT05034900.
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