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Home › Conditions › Bronchiectasis

Bronchiectasis

6 published articles · Updated continuously

Clinical Trial Landscape

Clinical Trials for Bronchiectasis

20 trials tracked for Bronchiectasis: 7 in phase 3 or 4 and 3 with published results. The most-cited published study has 188 citations.

20Trials tracked
7Phase 3 & 4
0Recruiting
3With published results
Phase distribution
Phase 4 1 Phase 3 6 Phase 2 6 Other / NA 7
  1. Phase 3 Ciprofloxacin Dry Powder for Inhalation in Non-cystic Fibrosis Bronchiectasis (Non-CF BE) Completed · 188 cited
  2. Phase 3 Ciprofloxacin Dry Powder for Inhalation (DPI) in Non-cystic Fibrosis Bronchiectasis (Non-CF BE) Completed · 184 cited
  3. Phase 3 Inhaled Mannitol as a Mucoactive Therapy for Bronchiectasis Completed · 168 cited
  4. Phase 4 Efficacy of Azithromycin in Treatment of Bronchiectasis Completed
  5. Phase 3 Safety and Effectiveness of AZLI (an Inhaled Antibiotic) in Adults With Non-Cystic Fibrosis Bronchiectasis Completed
  6. Phase 3 Safety and Effectiveness of AZLI (an Inhaled Antibiotic) in Adults With Non-Cystic Fibrosis Bronchiectasis Completed
Show 14 more trials
  1. Phase 3 EZ-2053 in the Prophylaxis of Acute Pulmonary Allograft Rejection Completed
  2. Phase 2 A Phase II , Placebo-controlled Study to Assess Efficacy of 28 Day Oral AZD9668 in Patients With Bronchiectasis Completed
  3. Phase 2 Evaluation of the Effect of AZD5069 in Patients With Bronchiectasis Completed
  4. Phase 2 A Study to Test How Well BI 1291583 is Tolerated by People With Cystic Fibrosis Bronchiectasis (Clairafly™) Completed
  5. Phase 2 Safety and Tolerability Study of 2 Dose Level of Arikayce™ in Patients With Bronchiectasis and Chronic Infection Due to Pseudomonas Aeruginosa. Completed
  6. Phase 2 Evaluation of Cipro Inhale in Patients With Non-cystic Fibrosis Bronchiectasis Completed
  7. Phase 2 Evaluation of the Quality of Life Questionnaire-Bronchiectasis (QOL-B) in Patients With Bronchiectasis Completed
  8. N/A Comparative Effectiveness and Safety of Inhaled Corticosteroids and Antimicrobial Compounds for Non-CF Bronchiectasis Completed
  9. N/A Effect of HFCWO Vests on Spirometry Measurements Completed
  10. N/A Assessment of an Exhaled Breath Test to Detect Bronchiectasis Completed
  11. N/A Ex-vivo Perfusion and Ventilation of Lungs Recovered From Non-Heart-Beating Donors to Assess Transplant Suitability Completed
  12. N/A Effects of Inspiratory Muscle Training in Patients With Bronchiectasis Completed
  13. N/A Can we Reduce Hospital Attendance Without Compromising Care by the Use of Telephone Consultation Completed
  14. N/A Effect of High Frequency Chest Wall Oscillation Vests on Spirometry Measurements Completed

Showing the 20 most-cited and recently-updated of 20 trials. Browse the full registry →

Trial data sourced from ClinicalTrials.gov. Counts describe the research landscape and are not a treatment recommendation. Informational only — not medical advice.

HCP Mode — summaries include clinical detail, trial data, and statistical outcomes.
Patient Mode — summaries use plain language, avoiding clinical jargon.
Immediate smoking cessation support increases 12-month quit rates in adults with chronic airway diseases
Allergy & Immunology RCT
Immediate smoking cessation support increases 12-month quit rates in adults with chronic airway diseases Scheduling Quit Appointments Now Boosts Long-Term Success For Asthma Patients
This randomized trial in 397 adult smokers with asthma, COPD, or bronchiectasis compared immediate support with usual advice. The immediate …
Scheduling a quit clinic visit immediately after diagnosis doubles long-term success rates for people with asthma or COPD.
May 15, 2026
Expert consensus guidelines for N-acetylcysteine use in various respiratory conditions
Rheumatology Guideline
Expert consensus guidelines for N-acetylcysteine use in various respiratory conditions Experts share new guidance on using N-acetylcysteine for lung health
This expert consensus guideline reviews the clinical utility of N-acetylcysteine (NAC) across several respiratory diseases. The authors sugg…
Medical experts have reached a consensus on how a specific supplement might help people managing various chronic lung diseases.
Frontiers May 4, 2026
Relaxation training and early benzodiazepines linked to respiratory recovery in adults with COPD, pneumonia, asthma, bronchiectasis, or interstitial lung disease
Rheumatology Cohort
Relaxation training and early benzodiazepines linked to respiratory recovery in adults with COPD, pneumonia, asthma, bronchiectasis, or interstitial lung disease Could early sedatives be slowing down lung recovery for adults with breathing problems?
This retrospective observational study examined 389 consecutive adults (≥ 18 years) admitted with chronic obstructive pulmonary disease, pne…
Early sedatives given to adults with breathing problems may slow lung recovery, making it harder for patients to improve before leaving the …
Frontiers Apr 18, 2026
Rapamycin therapy reduced infections and lymph node size in a female child with APDS1
Rheumatology Sys. Review
Rapamycin therapy reduced infections and lymph node size in a female child with APDS1 Neck Mass Was Not Cancer, It Was This Rare Condition
This case report describes a single female patient with Activated phosphoinositide 3-kinase delta syndrome type I (APDS1) who received rapam…
A rare genetic immune disorder caused a neck mass mistaken for cancer, ending years of failed treatments for recurrent lung infections and s…
Frontiers Apr 11, 2026
Rehabilitation interventions improve functional outcomes in bronchiectasis patients, though implementation remains inconsistent across clinical settings
Physical Medicine & Rehab Guideline
Rehabilitation interventions improve functional outcomes in bronchiectasis patients, though implementation remains inconsistent across clinical settings Why is rehab for bronchiectasis recommended but hard to get?
This mini review examines contemporary evidence on rehabilitation interventions for patients with bronchiectasis.
Pulmonary rehab is a proven standard for bronchiectasis patients, yet access to these life-improving programs remains limited and inconsiste…
Frontiers Apr 6, 2026
OPEP device added to chest physiotherapy improves adherence but not clinical outcomes in children with bronchiectasis
Pediatrics RCT
OPEP device added to chest physiotherapy improves adherence but not clinical outcomes in children with bronchiectasis Adding a breathing device to chest physiotherapy improved adherence but not clinical outcomes in children with bronchiectasis
In a randomized trial of 42 children with bronchiectasis, an 8-week multicomponent chest physiotherapy program improved exercise capacity an…
Adding a breathing device to chest physiotherapy helped children stick to their routine but offered no extra lung benefits for those with br…
Apr 3, 2026

Questions about Bronchiectasis

Does adding an OPEP device to chest physiotherapy help children with bronchiectasis?

Adding an OPEP device to chest physiotherapy does not improve exercise capacity or lung function in children with bronchiectasis, but it may increase adherence to therapy.

Full answer →