This study combined a case report with a review of English-language literature to evaluate 10 cases involving full-term male neonates. The conditions included neonatal mature teratoma, intra-abdominal cryptorchid testis, and testicular torsion. Surgical intervention consisted of excision performed either via laparoscopic surgery or laparotomy.
Pathological assessment revealed that mature teratomas were the predominant finding, accounting for 90.0% of the cases. Conversely, tumor torsion was observed in 20.0% of the cohort. Regarding the surgical approach, 40.0% of cases underwent laparoscopic surgery while 60.0% required laparotomy. All patients experienced uneventful recovery, and serum alpha-fetoprotein levels demonstrated a physiological decline consistent with postnatal age-related maturation.
No recurrences were reported during the one-month follow-up period. No adverse events, serious adverse events, or discontinuations were documented in this small series. The study notes that tumor growth was progressive in some instances, highlighting the need for timely intervention. However, the absolute numbers for specific outcomes were not reported in the source data.
The practice relevance suggests that evaluation of testicular position should be routine in male neonates with intra-abdominal masses, and gonadal tumors should be included in the differential diagnosis. Multidisciplinary, individualized management is essential for optimizing outcomes. Given the observational nature of the data and the small sample size, these findings should be interpreted with caution.
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IntroductionThis study investigated the clinical characteristics, diagnostic considerations, and optimal management of a neonatal mature teratoma arising from an intra-abdominal cryptorchid testis complicated by torsion, a rare clinical entity.MethodsWe retrospectively analyzed data from a full-term male neonate admitted in November 2025 with a prenatally detected intra-abdominal mass, including postnatal imaging, tumor marker assessment, surgical excision, and pathological confirmation. Concurrently, we conducted a systematic review of English-language literature using PubMed, Embase, Cochrane Library, and Web of Science.ResultsThe patient was diagnosed with a mature teratoma originating from an intra-abdominal cryptorchid testis. Intraoperative findings revealed 360° clockwise torsion causing colonic compression. Complete resection resulted in an uneventful recovery, with a physiological decline in serum alpha-fetoprotein (AFP) levels consistent with postnatal age-related maturation, and no recurrence at one-month follow-up. The literature review identified ten cases (including the present case) of prenatally detected ultrasound-detected tumors with progressive tumor growth. Surgical management primarily involved laparoscopic surgery (40.0%) or laparotomy (60.0%). Mature teratomas were the predominant pathology (90.0%), tumor torsion occurred in 20.0% of cases, and no recurrences were reported, indicating a favorable prognosis.ConclusionNeonatal mature teratomas arising from an intra-abdominal cryptorchid testis with torsion are exceedingly rare. Evaluation of testicular position should be routine in male neonates with intra-abdominal masses, and gonadal tumors should be included in the differential diagnosis. Multidisciplinary, individualized management is essential for optimizing outcomes.